Org 28312

Org 28312 is a drug developed by Organon International which acts as a potent cannabinoid receptor full agonist at both the CB₁ and CB₂ receptors. It was developed with the aim of finding a water-soluble cannabinoid agonist suitable for intravenous use as an analgesic, but did not proceed to human trials, with the related compound Org 28611 chosen instead due to its better penetration into the brain. The structure-activity relationships of these compounds have subsequently been investigated further leading to the development of a number of more potent analogues, derived by cyclisation around the indole or piperazine rings.

See also

References

.org

The domain name org is a generic top-level domain (gTLD) of the Domain Name System (DNS) used in the Internet. The name is truncated from organization. It was one of the original domains established in 1985, and has been operated by the Public Interest Registry since 2003. The domain was originally intended for non-profit entities, but this restriction was not enforced and has been removed. The domain is commonly used by schools, open-source projects, and communities, as well as by for-profit entities. The number of registered domains in org has increased from fewer than one million in the 1990s, to ten million as of June, 2012.

History

The domain org was one of the original top-level domains, with com, us, edu, gov, mil and net, established in January 1985. It was originally intended for non-profit organizations or organizations of a non-commercial character that did not meet the requirements for other gTLDs. The MITRE Corporation was the first group to register an org domain with mitre.org in July 1985. The TLD has been operated since January 1, 2003 by Public Interest Registry, who assumed the task from VeriSign Global Registry Services, a division of Verisign.

List of Power Rangers Wild Force characters

Power Rangers Wild Force is the 2002 Power Rangers season that tells the story of the Wild Force Power Rangers and their fight against the polluting Orgs.

Wild Force Power Rangers

The Wild Force Rangers are granted mystical powers and charged to protect the Earth from pollution-created creatures called Orgs. More specifically, they defend the fictional city of Turtle Cove, and are stationed aboard a flying island called the Animarium. Their mentor is Princess Shayla, and her mentor is Animus (who is an ancient Megazord). The Rangers represent the Ancient Animarium Warriors who also fought to destroy the Orgs and save the Earth.

The Rangers morph using devices known as Growl Phones (which have three operating modes: normal, human-form, and Power Animal Mode that resembles an animal). Each Ranger is also armed with a Crystal Saber (into which an Animal Crystal is inserted to call a Wild Zord). In addition to piloting their Zords (known as Wild Zords), the Rangers pilot other vehicles, known as the Soul Bird and the Savage Cycles. When the Rangers put their weapons together they create the Jungle Sword, which can be used by the Red Ranger to defeat certain enemies.

8664

8664 is a grassroots campaign located in Louisville, Kentucky. Its stated mission is "to advocate for the revitalization of Louisville through the removal of Interstate 64 (I-64) along the riverfront and the adoption of a transportation plan that will provide long-term benefits to the region's citizens, neighborhoods, environment and economy."

The movement wishes to alter plans for Louisville's interstates, formally referred to as the Ohio River Bridges Project, with three major components:

8664 proponents hope that the implementation of their plan will expand interest in Louisville's waterfront and reduce the need for a new downtown bridge, which would negatively impact Butchertown and the Old Jeffersonville Historic District in Jeffersonville, Indiana. 8664's plan would also involve extending the city's flagship Waterfront Park to the west side of downtown Louisville.