Thursday, 20 February 2025

Opiate

Opiates are analgesic alkaloid compounds found naturally in the opium poppy plant Papaver somniferum. The psychoactive compounds found in the opium plant include morphine, codeine, and thebaine. The term opiate should be differentiated from the broader term opioid, which includes all drugs with opium-like effects, including opiates, semi-synthetic opioids derived from morphine (such as heroin, hydrocodone, hydromorphone, oxycodone, and oxymorphone), and synthetic opioids which are not derived from morphine (such as fentanyl, buprenorphine, and methadone). All opioids, including the opiates, are considered drugs of high abuse potential and are listed under the Controlled Substances Act.

In 2013 between 13 and 20 million people used opiates recreationally (0.3% to 0.4% of the global population between the ages of 15 and 65).

Overview

Opiates belong to the large biosynthetic group of benzylisoquinoline alkaloids, and are so named because they are naturally occurring alkaloids found in the opium poppy. The major psychoactive opiates are morphine, codeine, and thebaine. Papaverine, noscapine, and approximately 24 other alkaloids are also present in opium but have little to no effect on the human central nervous system, and as such are not considered to be opiates. Very small quantities of hydrocodone and hydromorphone are detected in assays of opium on rare occasions; it appears to be produced by the plant under circumstances and by processes which are not understood at this time and may include the action of bacteria. Dihydrocodeine, oxymorphol, oxycodone, oxymorphone, metopon and possibly other derivatives of morphine and/or hydromorphone also are found in trace amounts in opium.

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Latest News for: opiates

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What to Know About Buprenorphine, Which Could Help Fight Opioid Crisis?

New York Times 17 Feb 2025

This medicine may be one of the best tools doctors have to fight the fentanyl crisis ... .

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An Effective Treatment for Opioid Addiction Exists. Why Isn’t It Used More?

New York Times 16 Feb 2025

A drug called buprenorphine may be the best tool doctors have to fight the fentanyl crisis. Why hasn’t it been more widely adopted? ... .

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Barbara Kingsolver Uses ‘Demon Copperhead’ Royalties to Build Rehab Center

New York Times 07 Feb 2025

Barbara Kingsolver has put royalties from her Pulitzer Prize-winning novel to work in the region it portrayed, starting a home for women in recovery ... .

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Intoxicated drivers arrested in Laois tested positive for cocaine, opiates and cannabis

Irish Independent 05 Feb 2025

Multiple drivers were arrested by Gardaí in Co ...

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Opiate War: US-China In A Fearsome Fentanyl Fight

MENA FN 31 Jan 2025

(MENAFN - Asia Times) United States President Donald Trump recently threatened to impose an additional 10% tariff on goods coming from China in response to the illegal import into the US of the ... .

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FDA Approves Journavx Drug to Treat Pain Without Addiction Risk

New York Times 30 Jan 2025

The drug, by Vertex Pharmaceuticals, blocks pain signals to the brain, making it nonaddictive ... .

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Latest News for: opiates

What to Know About Buprenorphine, Which Could Help Fight Opioid Crisis?

An Effective Treatment for Opioid Addiction Exists. Why Isn’t It Used More?

Barbara Kingsolver Uses ‘Demon Copperhead’ Royalties to Build Rehab Center

Intoxicated drivers arrested in Laois tested positive for cocaine, opiates and cannabis

Opiate War: US-China In A Fearsome Fentanyl Fight

FDA Approves Journavx Drug to Treat Pain Without Addiction Risk

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