Oocyte

An oocyte (UK /ˈəsʌɪt/, US /ˈ..st/), oöcyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia. During oogenesis, the oogonia become primary oocytes.

Formation

The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. Oogenesis results in the formation of both primary oocytes during fetal period, and of secondary oocytes after it as part of ovulation.

Characteristics

Cytoplasm

Oocytes are rich in cytoplasm, which contains yolk granules to nourish the cell early in development.

Nucleus

During the primary oocyte stage of oogenesis, the nucleus is called a germinal vesicle.

The only normal human type of secondary oocyte has the 23rd (sex) chromosome as 23,X (female-determining), whereas sperm can have 23,X (female-determining) or 23,Y (male-determining).

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The TRPV3 channel is a mediator of zinc influx and homeostasis in murine oocytes

PNAS 01 Apr 2025
Among the transition metals, oocytes exhibit high concentrations of ...
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