Tropisetron

Tropisetron (INN) is a serotonin 5-HT₃ receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. The drug is available in a 5 mg oral preparation or in 2 mg intravenous form. It is marketed by Novartis in Europe, Australia, New Zealand, Japan, South Korea and the Philippines as Navoban, but is not available in the U.S. It is also available from Novell Pharmaceutical Laboratories and marketed in several Asian countries as Setrovel.

Pharmacology

Tropisetron acts as both a selective 5-HT₃ receptor antagonist and α₇-nicotinic receptor agonist.

Adverse effects

Tropisetron is a well-tolerated drug with few side effects. Headache, constipation, and dizziness are the most commonly reported side effects associated with its use. Hypotension, transient liver enzyme elevation, immune hypersensitivity syndromes and extrapyramidal side effects have also been associated with its use on at least one occasion.There have been no significant drug interactions reported with this drug's use. It is broken down by the hepatic cytochrome P450 system and it has little effect on the metabolism of other drugs broken down by this system.

ICS 219

A ICS Form 219, Resource Status Card or T-Card, is a simple tool to record and track the location and status of individuals, teams, vehicles, and other equipment. It is part of the standardised Incident Command System now widely used by police, fire departments, and emergency management agencies to manage their responses to incidents.

The cards are so-named because they are made of card stock and have a T-like shape. These cards are displayed in resource status or “T-Card racks” (typically a sheet of plastic or metal with slots cut to accept the body of the card) where they can be easily viewed, retrieved, updated, and statused during the course of the incident.

T-Card Design

Each card is printed in a different color of card stock and used for a different resource category, kind, or type:

Weekend (Earth and Fire song)

"Weekend" is a song from 1979 by Dutch band Earth and Fire. It was written by guitarist Gerard Koerts for the album Reality Fills Fantasy.

Earth and Fire version

"Weekend" was released by Earth and Fire as a single in November 1979 and reached the number one spot in the singles charts in the Netherlands, Switzerland, Germany, Denmark and Portugal.

Track listing

Chart performance

Chips version

Weekend was first covered by the Swedish group Chips on their eponymously titled debut-album. Originally, the version was recorded in 1980, but was only available on the album's first printed issues, as all subsequent releases (now called "Sweets'n Chips") replaced the song with the track "Good Morning". It wasn't until the release of the 1997 Greatest Hits-album "20 bästa låtar" that the song became widely available again. The B-Side on the single was the Instrumental track "Tokyo".

Track listing

Scooter Version

"Weekend" was also covered by German techno group Scooter as "Weekend!". It was released in February 2003 as the first single from their 2003 album The Stadium Techno Experience. The single reached number 2 in the German Media Control Charts and was also a top-10 single in Norway, Austria, Denmark, the Netherlands, Finland and Sweden.

Weekend (Underground Lovers album)

Weekend is the eighth album by Australian indie rock/electronic band Underground Lovers, the band's first after a 12-year hiatus. It followed a reunion for Sydney and Melbourne performances at the 2009 Homebake festival and the release of their 2011 retrospective album, Wonderful Things. A Rubber Records media release said: "This led to sporadic carefully selected shows and the realisation that the band still had something to say."

"The moment we got back together it clicked", lyricist and vocalist Vincent Giarrusso told The Courier-Mail. "We did one rehearsal, we had six or seven song ideas and we went to the studio to record them. The first four songs on the album are from that initial recording and some of those are first takes. The song 'Can For Now', what you are hearing is the first time we played it." The band also reunited with producer Wayne Connolly, producer of their 1997 album Ways T' Burn, to get the guitar sounds they wanted.

Giarrusso said the album was inspired by the energy of director Jean-Luc Godard's 1960s cinema hit Weekend, and Godard's film was used in their video for "Au Pair".

Weekend (2011 film)

Weekend is a 2011 British romantic drama film directed by Andrew Haigh. It stars Tom Cullen and Chris New as two men who meet and begin a sexual relationship the week before one of them plans to leave the country. The film won much praise after premiering at the SXSW festival in the US, and was a success at the box office in the UK and the US, where it received a limited release.

Plot

On a Friday night in Nottingham, Russell attends a house party with friends. He assures his best friend Jamie that he will be there Sunday for his daughter's birthday. Russell leaves early, but decides to go to a gay club, alone and looking for a hookup. Just before closing time he meets Glen, a student artist, and they have sex back at Russell's apartment. The next morning, Glen coaxes a hesitant Russell to speak into a voice recorder about their experience the previous night. Glen tells him this is for an art project. The more reserved Russell is taken aback by Glen's blunt discussion of sex. After Russell finishes, they exchange numbers and Glen leaves. Russell is shown writing about Glen on his laptop, evidently something he does after each of his encounters.