ATN

ATN is the Sydney flagship television station of the Seven Network in Australia. The licence, issued to a company named Amalgamated Television Services, a subsidiary of Fairfax, was one of the first four licences (two in Sydney, two in Melbourne) to be issued for commercial television stations in Australia. It began broadcasting on 2 December 1956.

The station formed an affiliation with GTV-9 Melbourne in 1957, in order to share content. In 1963, Frank Packer ended up owning both GTV-9 and TCN-9, so as a result the stations switched their previous affiliations. ATN-7 and HSV-7 joined to create the Australian Television Network, which later became the Seven Network. ATN-7 is the home of the national level Seven News bulletins.

The studios and transmission tower

The station opened in 1956 with principal offices and studios located at Mobbs Lane, Epping (a suburb about 18 kilometres north west of Sydney). The initial black and white cameras and other equipment was supplied by the Marconi Company of England. Conversion to PAL colour occurred on 1 March 1975. Digital DVB-T commenced on 1 January 2001.

ATN1

Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. It is expressed in nervous tissue.

Function

Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Clinical significance

Mutations in ATN1 are associated with a form of trinucleotide repeat disorder known as "dentatorubral-pallidoluysian atrophy" or "dentatorubropallidoluysian atrophy".

Interactions

ATN1 has been shown to interact with:

References

Further reading

External links

Bis-choline tetrathiomolybdate

Bis-choline tetrathiomolybdate, or WTX101, is a salt of tetrathiomolybdate (TTM, MoS₄²⁻) and choline currently under investigation as a therapy against Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. Wilson disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. The disease is fatal if left undiagnosed and untreated. It is estimated that approximately 1 individual in every 15,000 worldwide have Wilson's disease, corresponding to approximately 30,000 individuals in the European Union and approximately 20,000 in the United States.

Bis-choline tetrathiomolybdate has been evaluated in clinical trials in patients with various forms of cancer and has received orphan designation in the US and EU as a potential therapy against Wilson disease.

Bis-choline salt of tetrathiomolybdate is a de-coppering therapy in clinical development against Wilson disease under the code name WTX101 by Wilson Therapeutics AB. Wilson Therapeutics was founded by HealthCap in 2012.

Omnia

Omnia may refer to:

See also

Omnia (musician)

Evgeny Smirnov (born May 18, 1987), primarily known by his stage name Omnia, is a trance and progressive music DJ and producer.

His DJ schedule has included festivals and clubs such as Global Gathering UK & Ukraine, Ultra Argentina, A State of Trance 600 Holland, Trancefusion Czech Republic, Summadayze, Zouk, Papaya, Privilege, Eden, Ageha and Ellui.

Life and career beginning

Still in his early 20's, Omnia's imagination was first captured by EDM sounds as a young boy in the late 1990s and early 2000s. By his late teens Omnia had started to experiment with music production with a particular love of trance, but with influences drawn from many genres that have been his passion for over a decade. Self-taught in the studio, Omnia's sound has a distinctive edge and a style that refuses to be pigeon holed. His productions started to gain international recognition in 2011 with the likes of Armin van Buuren and Markus Schulz supporting his early releases which included a remix of Arty & Mat Zo 'Rebound'.

Omnia (band)

Omnia is a self-described "neoceltic pagan folk" band based in the Netherlands and whose members over the years have had Irish, Dutch, Cornish, Belgian and Persian backgrounds. Their music takes on the form of various cultural routes, from places around the world such as Ireland, England, Cornwall and Persia.

They sing in English, Irish, Breton, Finnish, German, Dutch, Swedish, Latin and Hindi and play Celtic harp, mouth harp, hurdy-gurdy, bodhrán, guitar, bouzouki, didgeridoo, flutes of all kinds, bagpipes, various drums and percussion instruments.

Band line-up

Present band line-up