OSCAR (gene)

Osteoclast-associated immunoglobulin-like receptor is a protein that in humans is encoded by the OSCAR gene.

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References

Further reading

Oscar (opera)

Oscar is an American opera in two acts, with music by composer Theodore Morrison and a libretto by Morrison and English opera director John Cox. The opera, Morrison's first, is based on the life of Oscar Wilde, focused on his trial and imprisonment in Reading Gaol. It was a co-commission and co-production between The Santa Fe Opera and Opera Philadelphia (formerly the Opera Company of Philadelphia). This work received its world premiere at The Santa Fe Opera on 27 July 2013. Opera Philadelphia first presented the revised version of the opera on 6 February 2015.

The genesis of the opera resulted from a 2004 meeting in London between Morrison and Cox, after the premiere of Morrison's James Joyce song cycle, Chamber Music, which he wrote for countertenor David Daniels, a former student of his. Upon learning that Morrison had never composed an opera, but wished to write one for Daniels, Cox encouraged that idea. This led to correspondence between Cox and Morrison, and an agreement to collaborate on an opera based on the subject of Oscar Wilde. Cox and Morrison had each read the biography of Wilde by Richard Ellmann, and settled on a plan for co-authorship of an opera libretto based on the writings of Oscar Wilde and his contemporaries, with Walt Whitman serving as a chorus speaking from the realm of immortality. The opera used Wilde's poem "The Ballad of Reading Gaol", documents, letters, conversations and remarks by Wilde's contemporaries as source material for the libretto. Cox also consulted Merlin Holland, the grandson of Oscar Wilde and a scholar on Oscar Wilde.

NSW TrainLink H set

The NSW TrainLink H set or OSCAR (Outer Suburban CAR) is a class of electric multiple unit built by UGL Rail, Broadmeadow for CityRail in New South Wales, Australia. They are operated by NSW TrainLink. These sets operate services from Sydney to Hamilton (Newcastle), Springwood and Kiama. The first entered service in December 2006 and the last in December 2012. They are formed into 55 four-carriage sets.

The H sets are similar to the Fourth Generation Millennium Train but are more suited to longer distances, while the Millennium Trains are restricted to suburban runs on Sector 2. The layout and features of the OSCARs are similar to their predecessor the G sets. The OSCARs released some V sets to allow services to be built up to eight carriages and 1977 built DCM and DCT carriages to be withdrawn.

Design

There are many similarities between the OSCARs and the Millennium Trains, including improved external destination boards, internal destination boards displaying stopping patterns, Digital Voice Announcements and security cameras. The OSCARs also have additional features to increase comfort on the longer journeys they operate. These include high back seating covered with durable, vandal proof Woollen Moquette Fabric with padded head-rests, retractable footrests, luggage racks and a wheelchair-accessible toilet. Wheelchair seating is available in the vestibules, while 3x2 seating is provided in the upper and lower deck sections. Carriage interiors were designed by Transport Design International

The Prisoners (The Walking Dead)

The Prisoners are fictional characters from the comic book series The Walking Dead and the television series of the same name.

Comic book series

During Rick's coma, due to the news broadcasts, the inmates and guards had a basic understanding of what was going on. Soon, many of the guards abandoned the Prison and the inmates to fend for themselves; at about the same time, a few walkers had somehow gotten inside and began to kill the inmates. Several of the guards freed the inmates and joined together to fight their way out, resulting in heavy casualties. By the time Rick and his group discovered the Prison, it was discovered that there were only four survivors left who were locked up inside the cafeteria.

The two groups come into conflict after one of them, Thomas Richards, kills two of the survivors, Rachel and Susie Greene, Hershel Greene's two youngest twin daughters. Dexter is falsely accused of the crime due to him being the "only" prisoner who was arrested for murder (it is later revealed that Thomas was arrested for murder as well and initially lied about being arrested for committing tax fraud). Thomas also tries to kill Andrea who is left without an earlobe and two scars as well as Patricia. Rick saves Andrea who beats Thomas brutally, and the second attempted murder on Patricia's life is stopped by a vengeful Maggie, who empties her entire firearm clip into Thomas.

Eugene (given name)

Eugene is a common (masculine) first name that comes from the Greek εὐγενής (eugenēs), "noble", literally "well-born", from εὖ (eu), "well" and γένος (genos), "race, stock, kin".Gene is a common shortened form. The feminine variant is Eugenia or Eugénie.

Male foreign-language variants include:

Notable people

Christianity

Military

Gene (novel)

Gene is a thriller novel by Stel Pavlou (born 1970), published in 2005 in England by Simon & Schuster. It is published in several languages with some title changes. The Italian edition has the title La Conspirazione del Minotauro (The Minotaur Conspiracy). The novel is about a fictional New York detective, James North, who in the process of hunting down a criminal, uncovers a genetics experiment to unlock past lives through genetic memory, therefore achieving a kind of immortality. In so doing North discovers his own origins, that of a soldier from the Trojan War who is reincarnated seven times through history, forced to confront his nemesis each time, all for the loss of his one true love.

Characters

Cyclades (born circa 1300 BC)

Incarnations of Cyclades

Athanatos (born circa 1500 BC)

Incarnations of Athanatos

Gene (band)

Gene were an English alternative rock quartet that rose to prominence in the mid-1990s. Formed in 1993, they were popularly labelled as a Britpop band and often drew comparisons to The Smiths because of their Morrissey-esque lead singer, Martin Rossiter. Gene's music was influenced by The Jam, The Small Faces, The Style Council and The Clash.

History

The Go Hole and Spin

Gene's origins lie in a previous band which was first called The Go Hole, named after a fictional "Beat" club in John Clellon Holmes' novel Go, and later renamed Sp!n when they became a four piece. The band was formed by Lee Clark (vocals/guitar) and Daz Walton (bass). Soon afterwards, James joined on drums with John Mason on bass. Their first single recorded in the same studios as The Ruts' In a Rut' appeared on their own Big Pop Records label. A John Peel session fueled their early success where they mixed with the Camberwell scene mingling with members of House of Love, My White Bedroom and Vic Reeves and Bob Mortimer. Self-managed, apart from a couple of brushes with mini music moguls (in their own minds), John Mason would organise and negotiate much of the group's gigs, contracts and press especially later when they were a four piece. After 18 months Clark, Mason and James invited John's brother Steve Mason to play lead/rhythm guitar and thereby free Clark to focus on vocal style.