ORC2
Origin recognition complex subunit 2 is a protein that in humans is encoded by the ORC2 (ORC2L) gene.
Function
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, ORC4, and ORC5. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.
Interactions
ORC2 has been shown to interact with:
Podcasts:
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by Eric Lee
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by Eric Lee
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by Eric Lee
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by Eric Lee
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by Eric Howl
Forever Yours
by: Eric LeeI never thought
Love was so powerful
I saw love in your eyes
As if you saw it in mine
If you died in my arms
I'd never live
For you had brought me back to life
Fresh as a flower
Sweeter than candy and juice
Heart of gold
I'll never turn you loose
Even in the darkest nights
Your love glows so bright
Never will I leave you
For I wouldn't live without you
I would die in sorrow and sadness
No other girl would ever compare to you
You're unique and special
And beautiful, my boo
I wouldn't miss a single second
To look at your gorgeous face
To cherish and hold forever
Kiss my love and embrace (my love)