The Domain Name System of the Internet consists of a set of top-level domains which constitute the root domain of the hierarchical name space and database. In the growth of the Internet, it became desirable to expand the set of initially six generic top-level domains in 1984. As a result new top-level domain names have been proposed for implementation by ICANN. Such proposals included a variety of models ranging from adoption of policies for unrestricted gTLDs that could be registered by anyone for any purpose, to chartered gTLDs for specialized uses by specialized organizations. In October 2000, ICANN published a list of proposals for top-level domain strings it had received.
Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.
Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module, and components of this submodule act together in a gene-regulatory programme to suppress smooth muscle cell differentiation. Thus, mammalian Mediator subunit Med28 functions as a repressor of smooth muscle-cell differentiation, which could have implications for disorders associated with abnormalities in smooth muscle cell growth and differentiation, including atherosclerosis, asthma, hypertension, and smooth muscle tumours.
MED28 has been shown to interact with Merlin,Grb2 and MED26.
This article incorporates text from the public domain Pfam and InterPro IPR021640
Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.
This family of proteins represent the transcriptional mediator protein subunit 6 that is required for activation of many RNA polymerase II promoters and which are conserved from yeast to humans.
MED6 has been shown to interact with:
This article incorporates text from the public domain Pfam and InterPro IPR007018
(Asshole Records Intro)
(Chorus) x2
Why Why Why Why (That's Oakland)
Yee Yee Yee Yee (That's Richmond)
Hey Hey (That's Frisco)
And if you ain't from the Bay now your ass know
(Left)
Now somebody told me not to rep the Bay
Why not? This is where I stay
They said we was dead and stuck in a grave
And living off songs we made back in the day
So i'm gonna take the book and start turning pages
And expose the fact that they stealing Bay shit
And I ain't talking about popping collars and slanguage
I'm talking about the moves they made to make it
Artist making labels started with P for sure
That's Bay, we all entrepreneurs
We all doing our thing because Bay niggaz ain't no punks
Distribution popping outta the trunk
Partner, and don't think we see the relation
Between radio, mixtapes, and compiliations
And how you come out here on our radio stations
And say you love the Bay but can't name the places
(Yeah)
(Chorus) x2
(Locksmith)
Yo, we got a little dilemma, man
Niggaz are really bitter, they caught up in the mental, man
I'm in the middle it's about to give me a mental strain
Everybody's tickled but none of them niggaz get it, man
I know they just really wanna get rid of me
I'm not a victim, I listen as they belittle me
Then I just take the negative energy
Put it in my lyrics and spit it at my enemies
I disregard small affairs
Treat 'em like hopscotch and step all over squares
Scrutinizing me because I got the song on the air
But niggaz should understand that I belong over here
Yeah, nigga it's long overdue
They telling you different, then nigga it's far from the truth
In actuality, nigga, we starving like you
Nobody stepped up until we started to