NOTCH (magazine)

NOTCH is an Indian entertainment and lifestyle online magazine. It is part of privately held Pradeep Dadha Group of Companies, with Pradeep Dadha as chairman.NOTCH's corporate office is located in Chennai, India.

History

The online magazine was launched in September 2012, and the cover of the first issue featured Bollywood actress Kareena Kapoor. In addition to stories, the magazine includes multimedia content.

Target audience

NOTCH is geared to Indian consumers as well as non-resident Indians (NRI) living outside of India.

References

External links

Magazine

Magazines are publications, usually periodical publications, that are printed or electronically published (the online versions are called online magazines.) They are generally published on a regular schedule and contain a variety of content. They are generally financed by advertising, by a purchase price, by prepaid subscriptions, or a combination of the three. At its root, the word "magazine" refers to a collection or storage location. In the case of written publication, it is a collection of written articles. This explains why magazine publications share the word root with gunpowder magazines, artillery magazines, firearms magazines, and, in various languages although not English, retail stores such as department stores.

Definition

By definition, a "magazine" paginates with each issue starting at page three, with the standard sizing being 8 3/8" x 10 7/8". However, in the technical sense a "journal" has continuous pagination throughout a volume. Thus Business Week, which starts each issue anew with page one, is a magazine, but the Journal of Business Communication, which starts each volume with the winter issue and continues the same sequence of pagination throughout the coterminous year, is a journal. Some professional or trade publications are also peer-reviewed, an example being the Journal of Accountancy. Academic or professional publications that are not peer-reviewed are generally professional magazines. The fact that a publication calls itself a "journal" does not make it a journal in the technical sense. The Wall Street Journal is actually a newspaper.

Magazine (EP)

"Magazine" is the third extended play by Korean American singer Ailee. It was released on September 25, 2014, by YMC Entertainment and Neowiz Internet. Magazine saw Ailee take greater creative control, co-writing four of the album's five songs, including the album's title track; Ailee also collaborated with long-time producer Kim Do Hoon and Korean rap twosome, Dynamic Duo. The song "Don't Touch Me" was used to promote the EP.

Background and release

On September 15, 2014, it was revealed that Ailee will make her comeback on September 25 with her third EP Magazine. A teaser of the singer dressed as a clown with braided pigtails was released on the same day. The singer's agency also revealed that "Magazine" was an album that would present the singer in a matured light. On September 21, Ailee released the music video teaser for the EP's title track "Don't Touch Me". Two days later on September 23, the EP's album cover was released. On September 25, 2014, Ailee released "Magazine", digitally, as well as the music video for "Don't Touch Me". A comeback showcase was organised for the release of the album at Ilchi Art Hall in Cheongdamdong, Gangnam. In preparation for the album, the singer revealed that she lost 10 kilograms in one month for the album. She stated further that her company did not force her to lose the weight and that they had pushed an originally-scheduled comeback for early 2015 to September 2014. During an interview with After School Club, Ailee revealed Magazine was the hardest she had ever worked on an album; she stated further that she conceptualised Magazine as a whole.

Magazine (firearms)

A magazine is an ammunition storage and feeding device within or attached to a repeating firearm. Magazines can be removable (detachable) or integral to the firearm. The magazine functions by moving the cartridges stored in the magazine into a position where they may be loaded into the chamber by the action of the firearm. The detachable magazine is often referred to as a clip, although this is technically inaccurate.

Magazines come in many shapes and sizes, from those of bolt-action express rifles that hold only a few rounds to drum magazines for self-loading rifles that can hold as many as one hundred rounds. Various jurisdictions ban what they define as "high-capacity magazines".

Nomenclature

With the increased use of semi-automatic and automatic firearms, the detachable box magazine became increasingly common. Soon after the adoption of the M1911 pistol, the term "magazine" was settled on by the military and firearms experts, though the term "clip" is often used in its place (though only for detachable magazines, never fixed). The defining difference between clips and magazines is the presence of a feed mechanism in a magazine, typically a spring-loaded follower, which a clip lacks. Use of the term "clip" to refer to detachable magazines is a point of strong disagreement.

Neurogenic locus notch homolog protein 4

Neurogenic locus notch homolog 4 also known as notch 4 is a protein that in humans is encoded by the NOTCH4 gene located on chromosome 6.

Gene

An alternative splice variant of the NOTCH4 gene has been described, but its biological significance has not been determined.

Structure

The neurogenic locus notch homolog 4 protein is a member of the Notch family. Members of this type 1 transmembrane protein family share structural characteristics. These include an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain that consists of multiple, but different, domain types.

Function

Notch protein family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling pathway is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells

In Drosophilia, notch interacts with its cell-bound ligands (delta and serrate), and establishes an intercellular signaling pathway that then plays a key role in development. Homologues of the notch-ligands have also been identified in humans, but precise interactions between these ligands and the human notch homologues remain to be determined. The notch protein is cleaved in the trans-Golgi network, and then presented on the cell surface as a heterodimer. The protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal, and hepatic development.