Nike Shox

Shox is a shoe feature developed by Nike and incorporated in several of their flagship athletic sports shoes. Shox is an array of small hollow columns in the midsoles of the shoe, usually of rubber. There are different formations, but Shox are usually four circular columns in a square formation to provide cushioning. There can also be five or six Shox, 25 mm high, though they may vary in height, and triangular and rectangular Shox that Nike says provide better stability. Some shoes have midsoles made entirely of Shox, like the TL series.

Nike claims that Shox not only absorb impact from heel strike while running, but also claims they "spring back" and add more power to a runner's stride. Aside from this alleged boost in speed, the Shox is supposed to provide superior shock absorption with high-tech elastic foam.

The newer Shox series is compatible with "Nike+ technology." The Nike Shox Saya+ is the most recent Shox with this feature. The new Nike Shox Q'Vida Hi shoe is a new woman's "dance boot" implementation of Shox.

Shox

Shox: Rally Reinvented is an arcade-style rally game developed by EA Sports Big. It is available on the PlayStation 2 console in Europe, USA and Japan.

Gameplay

Shox: Rally Reinvented (Shox) features three environments where all tracks are based upon: Arid (a desert-like, sandy environment), Jungle (a jungle-themed, muddy environment), and Ice (an arctic, snowy and icy environment). In every track there are three "Shoxzones", areas the player must cross while being timed. When the player reaches the end of a Shoxzone, the player is rewarded with cash based on the time taken to cross it, divided into Gold, Silver and Bronze. However, if the player takes too long to cross the zone, beyond the Bronze time, a reward will not be given.

Shox also features the concept of a "Shoxwave", a sort of shockwave that follows the track ahead of the player's car if they successfully pass, within Gold time, through all three Shoxzones, and is activated on the next 'checkpoint' (for lack of a better word) (it is not required to achieve Gold time in each Shoxzone within a single lap). During the duration of its presence, the player will be continually earning cash, but the Shoxzone system will be temporarily disabled. The objective of the Shoxwave, should it be activated, is to drive fast enough to catch up to it before it reaches the next checkpoint. While approaching the Shoxwave, the screen will appear increasingly blurry and distorted and make driving at high speed more difficult. Should the player fail to catch up in time, the Shoxwave will disappear and the Shoxzone system will resume. On the other hand, if the player succeeds, the Shoxwave will speed ahead of the player upon passing the checkpoint, for the player to catch up to again.

Short stature homeobox gene

The short stature homeobox (SHOX) gene is a gene, located on both the X and Y chromosomes, which is associated with short stature in humans if mutated or present in only one copy (haploinsufficiency).

Pathology

The gene was first found during a search for the cause of short stature in women with Turner syndrome, in which there is loss of genetic material from the X chromosome, classically by loss of one entire X chromosome.

Since its discovery, the SHOX gene has been found to play a role in idiopathic short stature (short stature of unknown cause without other symptoms), Léri-Weill dyschondrosteosis, and Langer mesomelic dysplasia.

Gene dosage effects of extra copies of SHOX may be a cause of the increased stature seen in other sex chromosome aneuploidy conditions such as 47,XXX, 47,XYY, 47,XXY, 48,XXYY, etc.

Function

The SHOX gene is a homeobox gene, meaning that it helps regulate development. The SHOX gene is composed of 6 different exons and is located in the pseudoautosomal region (PAR1) of the X chromosome and Y chromosome. Experiments have found similar genes in a variety of animals and insects.

SHOX2

Short stature homeobox 2, also known as homeobox protein Og12X or paired-related homeobox protein SHOT, is a protein that in humans is encoded by the SHOX2 gene.

Function

SHOX2 is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA-binding domain. Homeobox proteins have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species.

Clinical significance

Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange Syndrome.

SHOX2 localises on chromosome 3, so it is an autosomal and not a pseudoautosomal homeobox (SHOX, which localises on the PAR1 region of chromosome X and Y, has a pseudoautosomal hereditability).

Nike

Nike may refer to:

Nike+

The Nike+iPod Sports Kit is an activity tracker device, developed by Nike, Inc., which measures and records the distance and pace of a walk or run. The Nike+iPod consists of a small transmitter device attached to or embedded in a shoe, which communicates with either the Nike+ Sportband, a receiver plugged into an iPod Nano, or directly with a 2nd Generation iPod Touch (or higher), iPhone 3GS, iPhone 4, iPhone 4S, iPhone 5, iPhone 5C, iPhone 5S, or a Nike+ Sportwatch. If using the iPod or the iPhone, iTunes software can be used to view the walk or run history.

The Nike+IPod was announced on 23 May 2006. On September 7, 2010, Nike released the Nike+ Running App (originally called Nike+ GPS) on the App Store, which used a tracking engine powered by MotionX that does not require the separate shoe sensor or pedometer. This application works using the accelerometer and GPS of the iPhone and the accelerometer of the iPod Touch, which does not have a GPS chip. Nike+Running is compatible with the iPhone 6 and iPhone 6 Plus down to iPhone 3GS and iPod touch. On June 21, 2012 Nike released Nike+ Running App for Android. The current app is compatible with all Android phones running 4.0.3 and up.

Nike, Inc.

Nike, Inc. (official, US /ˈnaɪki/; also, non-US /ˈnaɪk/) is an American multinational corporation that is engaged in the design, development, manufacturing and worldwide marketing and sales of footwear, apparel, equipment, accessories and services. The company is headquartered near Beaverton, Oregon, in the Portland metropolitan area. It is one of the world's largest suppliers of athletic shoes and apparel and a major manufacturer of sports equipment, with revenue in excess of US$24.1 billion in its fiscal year 2012 (ending May 31, 2012). As of 2012, it employed more than 44,000 people worldwide. In 2014 the brand alone was valued at $19 billion, making it the most valuable brand among sports businesses.

The company was founded on January 25, 1964, as Blue Ribbon Sports, by Bill Bowerman and Phil Knight, and officially became Nike, Inc. on May 30, 1971. The company takes its name from Nike, the Greek goddess of victory. Nike markets its products under its own brand, as well as Nike Golf, Nike Pro, Nike+, Air Jordan, Nike Blazers, Air Force 1, Nike Dunk, Air Max, Foamposite, Nike Skateboarding, and subsidiaries including Brand Jordan, Hurley International and Converse. Nike also owned Bauer Hockey (later renamed Nike Bauer) between 1995 and 2008, and previously owned Cole Haan and Umbro. In addition to manufacturing sportswear and equipment, the company operates retail stores under the Niketown name. Nike sponsors many high-profile athletes and sports teams around the world, with the highly recognized trademarks of "Just Do It" and the Swoosh logo.