Wikipedia does not have an encyclopedic article for Oma (suffix) (search results). You may want to read Wiktionary's entry on "-oma" instead. |
 |
https://wn.com/Oma_(suffix)
OMA
OMA or Oma may refer to:
Communication
Engineering
Entertainment
Medicine
OMA1
Metalloendopeptidase OMA1, mitochondrial is an enzyme that in humans is encoded by the OMA1 gene. As a Metalloprotease, this protein is a substantial component of the quality control system in the inner membrane of mitochondria. Being activated by enzyme Bax and Bak, mitochondrial protease OMA1 promotes cytochrome c release which subsequently induces apoptosis.
Structure
Gene
The gene OMA1 encodes a metalloprotease, a founding member of a conserved family of membrane-embedded metallopeptidases in mitochondria. The human gene has 9 exons and locates at chromosome band 1p32.2-p32.1
Protein
The human protein Metalloendopetidase OMA1, mitochondrial is 60 kDa in size and composed of 524 amino acids. The peptide fragment 1-13 is mitochondrial transition peptide, the mature protein has a theoretical PI of 9.35.
Function
The inner membrane of mitochondrial houses two AAA proteases and these membrane-embedded peptidases were termed m- and i-AAA proteases to indicate their different topology in the inner membrane. The m-AAA protease is facing the matrix and the i-AAA protease is facing the intermembrane space. OMA1 was shown to share an overlapping proteolytic activity with m-AAA protease. However, OMA1 doesn't completely regulate the turnover of a model substrate, Oxa1, as what the m-AAA protease does. On the contrary, Oma1 only generates N- and C-terminal proteolytic fragments. Recent study showed that the mammalian mitochondrial inner membrane fusion protein OPA1 can be degraded by OMA1 when mitochondria lose membrane potential or adenosine triphosphate. Such inducible proteolysis acts as a regulatory mechanism to proteolytically inactivate of OPA1, thus preventing the fusion of the mitochondrial network.
NIE
NIE or Nie or Nieh (before pinyin) may mean:
- Nie Er, Chinese composer
- Nie Rongzhen, Chinese Marshal
- Nie Ch'i-Kuei or Nieh Ch'i-Kuei (聶緝槼), Provincial Judge of Shanghai under Empress Dowager Cixi. Nieh was a son-in-law of Zeng Guofan (曾国藩)
- Nie Shicheng (Chinese: 聂士成), a Chinese general who served the Imperial government during the Boxer Rebellion
- Nie Dan (known as Daniel Nie ), a winner of 2000 Sam Ragan Awards, a leading Chinese-American artist
Nie (surname)
Nie (simplified Chinese: 聂; traditional Chinese: 聶; pinyin: Niè) is a Chinese surname. Nie is the 126th surname in the Hundred Family Surnames. It is spelled Nip in Cantonese.
Notable people named Nie
Notes
NIE (weekly magazine)
NIE (Polish for "No") is a Polish weekly magazine published in Warsaw.
History and profile
The magazine was first published in October 1990.Jerzy Urban is both the founder and editor-in-chief of the magazine.
Its political line is left. The magazine is very critical of right wing political vies and religion, especially Catholicism. In the 1990s it supported the leader of the Democratic Left Alliance, Aleksander Kwasniewski. It publishes lot of satirical texts with cartoons and pictures.
NIE has a circulation of 600,000 copies in 1991. In 1995 its circulation was over 700,000 copies.
In 1990 when Solidarity and the church were planning to push a strict new anti-abortion law through parliament, the magazine published a quarter-page, full-color photograph of a nude couple about to make love to warn its readers that "they risked going to jail or being forced into unwanted marriages if they did what the couple in the picture was about to do." The church leaders and President Lech Walesa harshly criticized it and in March 1991 the prosecutor's office charged Urban with "publishing an image of pornographic character."
