Neurogenic differentiation 1 (NeuroD1), also called β2, is a transcription factor of the NeuroD-type. It is encoded by the human gene NEUROD1.
It is a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
NEUROD1 has been shown to interact with MAP3K10,MAFA and Cyclin D1.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
(Eric Carmen)
Lovers come and lovers go
But it's never twice the same
Happiness is hard to show
When you're numb to all the pain
And I've been floatin' 'round
Like an old newspaper
Blowin' down some windy street
Feeling so alone and incomplete
But there's nowhere to hide
Where the night can't find me
Where the light of the sun can't blind me
Like the light in a woman's eyes
There's nowhere to hide
From the dream that drives me
Like a fire burning deep inside me
Oh, I know she'll be there tonight
Can the future be foretold
In a faded photograph
Can a dream be bought and sold
Well, I guess I have to laugh
Sippin' on a scotch and soda
A shadow in the corner booth
So philosophic and drunk on grown-up truth
But there's nowhere to hide
Where the night can't find me
Where the light of the sun can't blind me
Like the light in a woman's eyes
There's nowhere to hide
From the dream that drives me
Like a fire burning deep inside me
Oh, I know she'll be there tonight
Half-forgotten fragments
Of a high school dance
In the dead white hours of winter
When we loved so hard
That we thought it would never end
Tryin' to remember
How it used to feel
When a kiss was something special
And I wonder now
Will it ever be again
But there's nowhere to hide
Where the night can't find me
Where the light of the sun can't blind me
Like the light in a woman's eyes
There's nowhere to hide
From the dream that drives me
Like a fire burning deep inside me
Oh, I know she'll be there tonight
Lovers come and lovers go
But it's never twice the same
Happiness is hard to show
When you're numb to all the pain
And I've been floatin' round
Like an old newspaper
Blowin' down some windy street
Feeling so alone and incomplete
But there's nowhere to hide
Where the night can't find me
Where the light of the sun can't blind me
Like the light in a woman's eyes
There's nowhere to hide
From the dream that drives me
Like a fire burning deep inside me
Oh, I know she'll be there tonight