Nucleoporin 205

Nucleoporin 205 (Nup205) is a protein that in humans is encoded by the NUP205 gene.

Function

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPC's are composed of subcomplexes, and NUP205 is part of one such subcomplex.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Nucleoporin 88

Nucleoporin 88 (Nup88) is a protein that in humans is encoded by the NUP88 gene.

Function

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.

Interactions

NUP88 has been shown to interact with NUP98.

References

Further reading

Nucleoporin 188

Nucleoporin 188 (Nup188) is a protein that in humans is encoded by the NUP188 gene.

Function

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP188 is part of one such subcomplex.

References

This article incorporates text from the United States National Library of Medicine, which is in the public domain.