NKX3-2

NK3 homeobox 2 also known as NKX3-2 is a human gene. It is a homolog of bagpipe(bap) in Drosophila and therefore also known as Bapx1 (bagpipe homeobox homolog 1) . The protein encoded by this gene is a homeo domain containing transcription factor.

Function

NKX3-2 plays a role in the development of the skeleton. Nkx3-2 in mice also regulates patterning in the middle ear.<ref "pmid = 14973294"> Tucker AS, Watson RP, Lettice LA, Yamada G, Hill RE (2004). "Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution". Development 131 (6): 1235–1245. doi:10.1242/dev.01017. PMID 14973294. </ref>

References

External links