The nuclear-cytoplasmic ratio (also variously known as the nucleus:cytoplasm ratio, nucleus-cytoplasm ratio, N:C ratio, or N/C) is a measurement used in cell biology. It is a ratio of the size (i.e., volume) of the nucleus of a cell to the size of the cytoplasm of that cell.
The N:C ratio indicates the maturity of a cell, because as a cell matures the size of its nucleus generally decreases. So, for example, "blast" forms of erythrocytes, leukocytes, and megakaryocytes start with an N:C ratio of 4:1, which decreases as they mature to 2:1 or even 1:1 (with exceptions for mature thrombocytes and erythrocytes, which are anuclear cells, and mature lymphocytes, which only decrease to a 3:1 ratio and often retain the original 4:1 ratio).
An increased N:C ratio is commonly associated with precancerous dysplasia as well as with malignant cells.
Out the window
Look what's happening
In my prism watching day by
(Day by day)
In my humor
Kiss and make up friend
Out the window
Oh look what's happening
Give my time away
Give me all the time I pay
Kiss my cross away
I break down doors my candle whistles
Hello, hello, hope you're feeling fine
Hello, hello, hope you're feeling mine
Hello, hello, hope you're feeling fine
Hope you're feeling time
Out the window
Bring me back my rose I gave away
In a picture
A freckle and a famous feature
She's not smiling
Give my time away
Give me all the love you need
I want to watch you bloom and breathe
Kiss my mouth I hear you whistle
Hello, hello, hope you're feeling fine
Hello, hello, hope you're feeling mine
Hello, hello, hope you're feeling fine
Hope you're feeling time
Whistle down the wind
(Whistle softly)
Whistle down the wind
(Whistle softly)
Kiss and be my friend
(Whistle softly)