N.I.B.

"N.I.B." is a song released by the British heavy metal band Black Sabbath. It first appeared as the fourth track on the band's 1970 debut album, Black Sabbath. The lyrics are in the first person from the point of view of Lucifer. Lyricist Geezer Butler has said that "the song was about the devil falling in love and totally changing, becoming a good person."

"N.I.B." begins with a bass solo by Geezer Butler, titled "Bassically" on some US releases. It involves the use of wah-wah on his bass and was recorded in one take, as the amp's volume control is audibly turned up before the distorted bass intro of "N.I.B." begins.

The song's main riff (as well Osbourne's vocal delivery) have been noted for their Cream-influenced sound - the song has even been referred to as "the raucous defiling of Cream".

Title meaning

The title was widely rumoured to have stood for "Nativity in Black" (or to a much lesser extent, "Name In Blood"). In a 1992 interview, Geezer Butler states that the title simply refers to Bill Ward's goatee at the time, which the rest of the band thought was shaped like a pen nib; also referred to as nibby. Apparently, Geezer Butler said: "Originally it was Nib, which was Bill's beard. When I wrote N.I.B., I couldn't think of a title for the song, so I just called it Nib, after Bill's beard. To make it more intriguing I put punctuation marks in there to make it N.I.B. By the time it got to America, they translated it to Nativity In Black."

IB

IB, Ib or ib may refer to:

Places

Companies and organizations

Business and economics

Products and services

Interstate 895 (Maryland)

Interstate 895 (I-895) is an Interstate Highway in the U.S. state of Maryland. Known as the Harbor Tunnel Thruway, the highway runs 14.87 miles (23.93 km) between one junction with I-95 in Elkridge and another interchange with I-95 on the east side of Baltimore. I-895 is a toll road that crosses the Patapsco River estuary via the Baltimore Harbor Tunnel, connecting U.S. Route 1 (US 1), I-695, and the Baltimore–Washington Parkway in the southwestern suburbs of Baltimore with US 40 on the east side of Baltimore. In conjunction with a pair of spurs, unsigned I-895A and I-895B, I-895 provides access to the tunnel from I-97 and Maryland Route 2 (MD 2) in Glen Burnie. The highway is designed for through traffic by having partial interchanges that require vehicles from almost all starting points to pass through the tunnel and the tunnel toll plaza, where a $4 toll is charged to passenger vehicles, before exiting the facility.

NF-κB

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory.

Discovery

NF-κB was discovered by Dr. Ranjan Sen in the lab of Nobel Prize laureate David Baltimore via its interaction with an 11-base pair sequence in the immunoglobulin light-chain enhancer in B cells.

Structure