Moonwalker
Moonwalker, also known as Michael Jackson: Moonwalker, is a 1988 American anthology film starring Michael Jackson. Rather than featuring one continuous narrative, the film is a collection of short films about Jackson, several of which are long-form music videos from Jackson's Bad album. The film is named after the dance technique known as the moonwalk, which Jackson was known for performing in the 1980s. The name of the dance move was dubbed by the media, not by Jackson himself; however, he did choose the title of the film himself.
Plot segments
"Man in the Mirror"
The first segment of Moonwalker is a live performance of "Man in the Mirror" during his Bad Tour in Europe. Clips from Wembley Stadium among others can be seen. It also features a montage of clips of children in Africa, Martin Luther King Jr., Mother Teresa, Mahatma Gandhi, John Lennon, and other historical figures.
"Retrospective"
The second segment is a short biographical film about Jackson, covering the early years from the Jackson 5 until the Bad world tour. Excerpts of the following songs are played in the following order:
Michael Jackson's Moonwalker
Michael Jackson's Moonwalker is the name of several video games based on the 1988 Michael Jackson film Moonwalker. U.S. Gold published various games for home computers, released in 1989, whilst Sega developed two similarly themed beat 'em up video games in 1990; one released for arcades and another released for the Sega Genesis and Sega Master System. Each of the games' stories loosely follow the story of the film, in which Michael Jackson must rescue kidnapped children from the evil Mr. Big, and incorporate synthesized versions of the musician's hits, such as Beat It and Smooth Criminal. The games, particularly the Genesis adaptation, have achieved cult status.
Home computer versions
Versions of the game were released for the popular 8-bit and 16-bit home computers of the time. They were developed by two small software houses, Irish Emerald Software Ltd and American Keypunch Software, and published by U.K. company U.S. Gold. The home computer versions are the only games to make reference to the early portions of the film.
BTK
BTK may refer to:
Biology
Business
Music
Other
Birth Through Knowledge
Birth Through Knowledge (aka BTK) was a Canadian hip-hop/rock band best known for their 1998 single "Peppyrock," the video for which was nominated for the 1998 MuchMusic Best Video Award. The band consisted of Lo-Ki (vocals), Stone Groove (vocals), DJ Spinz (turntables), Adam Carlo (bass),Sam Cino (drums,percussion) and Matt deMatteo (drums).
After signing onto the Tommyboy/Ignition label, BTK released one album "Birth Thru Knowledge" in 1998.
BTK first came to attention when their song "Corncob Pipe" was included on the sampler disc that Korn released alongside Follow the Leader. They were the first indie band to ever open the main-stage at Edgefest '97. In 1998, the band toured with the Beastie Boys and with Our Lady Peace. They appeared in the 1998 Summersault tour.
The band won the 1997 MuchMusic Best Independent Video Award for "Superchile." They were also nominated for a Juno Award in 1999 in the Best Alternative Album category, losing to Rufus Wainwright.
Footnotes
Bruton's tyrosine kinase
Bruton's tyrosine kinase (abbreviated Btk or BTK) also known as tyrosine-protein kinase BTK is an enzyme that in humans is encoded by the BTK gene. BTK is a kinase that plays a crucial role in B-cell development.
Function
BTK plays a crucial role in B cell maturation as well as mast cell activation through the high-affinity IgE receptor.
Btk contains a PH domain that binds phosphatidylinositol (3,4,5)-trisphosphate (PIP3). PIP3 binding induces Btk to phosphorylate phospholipase C, which in turn hydrolyzes PIP2, a phosphatidylinositol, into two second messengers, inositol triphosphate (IP3) and diacylglycerol (DAG), which then go on to modulate the activity of downstream proteins during B-cell signalling.
Clinical significance
Mutations in the BTK gene are implicated in the primary immunodeficiency disease X-linked agammaglobulinemia (Bruton's agammaglobulinemia). Patients with XLA have normal pre-B cell populations in their bone marrow but these cells fail to mature and enter the circulation. The Btk gene is located on the X chromosome. At least 400 mutations of the BTK gene have been identified.
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