Sound

In physics, sound is a vibration that propagates as a typically audible mechanical wave of pressure and displacement, through a medium such as air or water. In physiology and psychology, sound is the reception of such waves and their perception by the brain.

Acoustics

Acoustics is the interdisciplinary science that deals with the study of mechanical waves in gases, liquids, and solids including vibration, sound, ultrasound, and infrasound. A scientist who works in the field of acoustics is an acoustician, while someone working in the field of acoustical engineering may be called an acoustical engineer. An audio engineer, on the other hand is concerned with the recording, manipulation, mixing, and reproduction of sound.

Applications of acoustics are found in almost all aspects of modern society, subdisciplines include aeroacoustics, audio signal processing, architectural acoustics, bioacoustics, electro-acoustics, environmental noise, musical acoustics, noise control, psychoacoustics, speech, ultrasound, underwater acoustics, and vibration.

Urethral sounding

Sounding or urethral sounding is the medical use of probes called sounds to increase the inner diameter of the urethra and to locate obstructions in it. Sounds are also used to stretch the urethra in order to receive genital piercing.

Urethral sounding and urethral play are also used to refer to this practice in a sexual context.

Urethral play can involve the introduction of either soft or rigid items into the meatus of the penis (as well as farther in). Objects such as sounds are usually only inserted about halfway into the glans and can usually be easily retrieved. Other toys and items, such as catheters, may be introduced deeper; in some cases even into the bladder. Some items may even be allowed to curl several times or expand within the bladder. This action in the male may be directly or indirectly associated with stimulation of the prostate gland and some types of bladder control.

Risks

If not conducted carefully, sounding carries a risk of irritation, tearing of the urethra, or of urinary tract infection. Infections may become serious if they progress to the bladder or kidneys, and should be referred to a doctor.

Sound (medical instrument)

In medicine, sounds are instruments for probing and dilating passages within the body, the best-known examples of which are urethral sounds and uterine sounds. Some people enjoy using them for urethral play.

Urethral sounds

Urethral sounds are designed to be inserted into the male or female urethra, for the purpose of stretching or unblocking a stricture. There are a number of different types of urethral sounds:

Uterine sounds

These sounds or dilators are intended for probing a woman's uterus through the cervix, to measure the length and direction of the cervical canal and uterus, to determine the level of dilation, or to induce further dilation.

Mind (charity)

Mind is a mental health charity in England and Wales. Founded in 1946 as the National Association for Mental Health (NAMH), it celebrated its 60th anniversary in 2006.

Mind offers information and advice to people with mental health problems and lobbies government and local authorities on their behalf. It also works to raise public awareness and understanding of issues relating to mental health. Since 1982, it has awarded an annual prize for "Book of the Year" having to do with mental health, in addition to three other prizes

Over 180 local Mind associations (independent, affiliated charities) provide services such as supported housing, floating support schemes, care homes, drop-in centres and self-help support groups. Local Mind associations are often very different in size, make up and character—it is a common misconception that they all work to the same policy and procedural framework. Mind is a national brand but all local associations are unique, although they do all sign up to certain shared aims and ethical guidelines.

Mind (The Culture)

In Iain M. Banks' Culture series, most larger starships, some inhabited planets and all orbitals have their own Minds: sentient, hyperintelligent machines originally built by biological species, which have evolved, redesigned themselves, and become many times more intelligent than their original creators.

These Minds have become an indispensable part of the Culture, enabling much of its post-scarcity amenities by planning and automating society (controlling day-to-day administration with mere fractions of their mental power). The main feature of these Minds—in comparison to extremely powerful artificial intelligences in other fiction—is that the Minds are (by design and by extension of their rational, but "humanistic" thought processes) generally a very benevolent presence, and show no wish to supplant or dominate their erstwhile creators. Though this is commonly viewed in a utopian light, a view where the human members of the Culture amount to little more than pets is not unsupportable.

MinD

The MinD protein is one of three proteins encoded by the minB operon and also a part of the ParA family of ATPases. It is required to generate pole to pole oscillations prior to bacterial cell division as a means of specifying the midzone of the cell. It is a peripheral membrane ATPase involved in plasmid partitioning.

History

When first discovered in E.coli, MinD was thought to associate with MinC and form a stable cap at each bacterial pole, thereby specifying the mid-zone of the cell by alleviating inhibitory pressures in that region. Through the use of live-cell imaging with GFP fusion proteins, Raskin and de Boer revealed a dynamic interaction of the Min proteins, demonstrating that MinC and MinD instead rapidly oscillate between the two poles in a non-static manner.

Function

The ATPase activity of MinD is activated by MinE while in the presence of phospholipids, suggesting that the binding to the membrane induces a conformational change allowing it to become susceptible to MinE activation. MinD activity is dependent on local MinD concentration, suggesting an oligomerization process and cooperativity.