MID

MID or Mid may refer to:

Computers and electronics

Medicine and biology

Military

MID1

Midline-1 is a protein that in humans is encoded by the MID1 gene.

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing; however, the full length nature of two variants has not been determined.

MID2

Midline-2 is a protein that in humans is encoded by the MID2 gene.

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Interactions

MID2 has been shown to interact with MID1.

References

Further reading

Day (automobile)

The Day Utility was an automobile manufactured in Detroit, Michigan by the Day Automobile Company from 1911-14. The Day used a four-cylinder, 30 horsepower (22 kW) engine and shaft drive. Removal of the rear seat and doors allowed the car to be converted from a five-seater touring car to a light truck in one minute. As a truck, the Day was able to carry up to 1,000 lb (450 kg) in a 36-inch (910 mm) by 96-inch (2,400 mm) cargo space. The rear seat could be lifted away by triggering two spring locks. The Day had an advertised price of $950US.

References

Day (Michelangelo)

Day is a marble sculpture by Michelangelo, datable to 1526–31. It is a pair with Night on the tomb of Giuliano de' Medici in the Medici Chapel in San Lorenzo in Florence.

External links

Day (surname)

Day is a surname. Notable people with the surname Day include:

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