Template:PBB/407043
MicroRNA 7-1 is a protein that in humans is encoded by the MIR7-1 gene.
microRNAs, or miRNAs, are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
[Verse 1]
You say you didn't need me
And now you're wondering
Why it is I'm sick of seeing your face
You say that all the things we
Did together was a way
To get your head out your mistakes
Now I have a conclusion
That by the time you realize
I'll be something in your eyes
I'll be close to you... yeah ooh
[Hook]
There's no turning back
No more wanting more
No more gaining, maintaining
It's not moving, I'm not using
It's abusing me...
(Don't stop now)
'Cause it's entertaining to
(Watch you down)
Knowing that there is no
(Way, no how)
For you to ever meet the way it should
(So I decided not to make that of what shouldn't be)
[Chorus]
If something is left, then put it to the test
Holding out your best is better than the rest
It's no contest, 'cause what you decided
Is gonna be the last one
And let the draining hang loose
Just drain it out, put it to good use
And let it fade out
Then move your pace right through the way
Make your way now
Make your way now
[Verse 2]
I get this crazy feeling
That what I'm doing is not what
You wanted me to do
But I don't take it so lightly
I replace myself with someone else
So you could be pleased
Now I have a conclusion
That by the time you realize
I'm not by your side
Ooh, I will be close to you, yeah
[Hook]
There's no turning back
No more wanting more
No more gaining, maintaining
It's not moving, I'm not using
It's abusing me...
(Don't stop now)
'Cause it's entertaining to
(Watch you down)
Knowing that there is no
(Way, no how)
For you to ever meet the way it should
(So I decided not to make that of what shouldn't be)
[Chorus]
If something is left, then put it to the test
Holding out your best is better than the rest
It's no contest, 'cause what you decided
Is gonna be the last one
And let the draining hang loose
Just drain it out, put it to good use
And let it fade out
Then move your pace right through the way
Make your way now
Make your way now
[Bridge]
Make your way now (x8)
(Ooh...)
The time will be, for you and me
To go away together
But that is gone, not to prolong
Inside, this is what I want to be
[Chorus]
If something is left, then put it to the test
Holding out your best is better than the rest
It's no contest, 'cause what you decided
Is gonna be the last one
And let the draining hang loose
Just drain it out, put it to good use
And let it fade out
Then move your pace right through the way
Make your way now