Kush
Kush or Cush may refer to:
Bible
Entertainment
People
Surname
Kush (band)
Kush was an American rap metal band formed in 2000 by rapper B-Real, Deftones guitarist Stephen Carpenter, and former Fear Factory members Raymond Herrera and Christian Olde Wolbers.
History
The project was first announced in 2000. "Dr. Kush" was chosen as an alternate name in case the original band name was already in use. In November 2000, it was reported that seven tracks had been completed. In 2001, B-Real expressed an interest in releasing the band's debut album by the following year or in 2003. Kush performed at the fifth annual Cypress Hill Smoke Out in 2002, opening with a song entitled "Psycho Killer", one of ten completed tracks that were prepared for an eventual album. B-Real stated that the band's music is "unlike any other rap-metal type stuff. It's a little bit more aggressive. And the way I attack it from a lyrical standpoint is totally different from what I do with Cypress. Cypress is more street-orientated. With Kush, it's a little bit of everything." In April 2002, it was reported that Kush had completed its debut album, but that it would be difficult to release because all of the band members were signed to different labels. In November 2002, it was reported that the album was not completed, but that it was getting close to completion. To date, no material from the band has been released officially, but demos have been leaked on various file sharing sites.
Kush (satrapy)
Kush was a satrapy of the Achaemenid Empire. The territory was conquered from the Nubians.
MGMT
MGMT is an American rock band formed in 2002 by Benjamin Goldwasser and Andrew VanWyngarden. After the release of their first album, the members of their live band, Matthew Asti, James Richardson and Will Berman, joined the core band in the studio. Formed at Wesleyan University and originally with Cantora Records, they signed with Columbia Records and Red Ink in 2006.
On October 5, 2007, Spin.com named MGMT "Artist of the Day." On November 14, 2007, Rolling Stone pegged MGMT as a top ten "Artist to Watch" in 2008. The band was named ninth in the BBC's Sound of 2008 Top Ten Poll. They were also named as Last.fm's most played new artist of 2008 in their Best of 2008 list.
MGMT's first album, Oracular Spectacular, debuted at No. 12 on the UK album chart, No. 13 after 34 weeks in the New Zealand RIANZ charts, number six on the Australian ARIA Charts, and hit number one on the Billboard Top Heatseekers chart. It has also been named the 18th best album of the 2000s by Rolling Stone magazine. It was named the best album of 2008 by NME. MGMT also appeared prominently in Australia's Triple J Hottest 100 2008, coming in 2nd with "Electric Feel", 5th with "Kids" and 18th with "Time to Pretend".
O-6-methylguanine-DNA methyltransferase
O6-alkylguanine DNA alkyltransferase (also known as AGT, MGMT or AGAT) is a protein that in humans is encoded by the O6-methylguanine DNA methyltransferase (MGMT) gene. O6-methylguanine DNA methyltransferase is crucial for genome stability. It repairs the naturally occurring mutagenic DNA lesion O6-methylguanine back to guanine and prevents mismatch and errors during DNA replication and transcription. Accordingly, loss of MGMT increases the carcinogenic risk in mice after exposure to alkylating agents. The two bacterial isozymes are Ada and Ogt.
Function and mechanism
Although alkylating mutagens preferentially modify the guanine base at the N7 position, O6-alkyl-guanine is a major carcinogenic lesion in DNA. This DNA adduct is removed by the repair protein O6-alkylguanine DNA alkyltransferase through an SN2 mechanism. This protein is not a true enzyme since it removes the alkyl group from the lesion in a stoichiometric reaction and the active enzyme is not regenerated after it is alkylated (referred to as suicide enzyme). The methyl-acceptor residue in the protein is a cysteine.
MGMT (album)
MGMT is the self-titled third studio album by American band MGMT released on September 17, 2013.
The album features a variety of unique visual elements to accompany and illuminate the new music via "The Optimizer", which provides listeners a simultaneously aural and optical listening experience featuring video and CGI work, and is available as part of an enhanced album package on all commercial formats.
History
On September 27, 2010, an interview article in Spin quoted them as saying that they will have less freedom on this album, claiming that Columbia was not happy with the reception of the band's second album, Congratulations. MGMT later denied these statements in an email to Pitchfork, who cited the article on their own site as a side note to a different story, stating that they were not "even close to starting the process of making a new album," that "label-relations are currently quite friendly," and finally telling readers "Don't believe everything that you read (even on Pitchfork.com)."
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