MCM5

DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene.

Function

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

See also

  • Mini Chromosome Maintenance
  • Interactions

    MCM5 has been shown to interact with:

  • Cell division cycle 7-related protein kinase,
  • MCM2,
  • MCM3,
  • MCM7,
  • ORC2L,
  • ORC6L, and
  • STAT1.
  • References

    Further reading


    PABCO Transit

    PABCO Transit, Inc., (now NJ Transit Morris, Inc.) doing business under the Morris County Metro brand, was a public transport company based in Dover, New Jersey operating local bus service in Morris County for New Jersey Transit. The company was originally called Passaic - Athena Bus Lines which operated service in Passaic and Clifton, New Jersey.

    Passaic-Athenia Bus Co.

    The Passaic-Athenia Bus Co. (originally Red Star Transportation up until 1922) operated the following routes prior to NJ Transit's takeover and contracting of the routes. The 702 was co-operated with Garfield & Passaic Transit as their #6 route and Community as its #1 route.

    Morris County Metro

    Renumbered routes

    In October 2010, New Jersey Transit decided to take over these routes and split them into routes 871875 and 880 by a newly created subsidiary called NJ Transit Morris, Inc. Morris County still subsidizes their operation. These routes are part of the Central Division.

    Previously discontinued routes

    On June 1, 2010 New Jersey Transit has decided to stop subsidizing the following routes leading to their discontinuation at the end of June.

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