Materia medica (English: medical material/substance) is a Latin medical term for the body of collected knowledge about the therapeutic properties of any substance used for healing (i.e., medicines). The term derives from the title of a work by the Ancient Greek physician Pedanius Dioscorides in the 1st century AD, De materia medica, 'On Medical Material' (Περὶ ὕλης ἰατρικῆς in Greek). The term materia medica was used from the period of the Roman Empire until the 20th century, but has now been generally replaced in medical education contexts by the term pharmacology.
The earliest known writing about medicine was a 110-page Egyptian papyrus. It was supposedly written by the god Thoth in about 16 BC. The Ebers papyrus is an ancient recipe book dated to approximately 1552 BC. It contains a mixture of magic and medicine with invocations to banish disease and a catalogue of useful plants, minerals, magic amulets and spells. The most famous Egyptian physician was Imhotep, who lived in Memphis around 2500 B.C. Imhotep’s materia medica consisted of procedures for treating head and torso injuries, tending of wounds, and prevention and curing of infections, as well as advanced principles of hygiene.