Magnificent may refer to:
Magnificent! is an album by pianist Barry Harris recorded in 1969 and released on the Prestige label.
Allmusic awarded the album 4 stars with its review by Jim Todd stating, "Magnificent brilliantly illustrates Barry Harris' unique rapport with the bop piano tradition. Absolutely unlike the enervating, curatorial approach of the neo-con movement, Harris deals with the tradition as a continuum, perpetually rejuvenating and extending it".The Penguin Guide to Jazz identified it as part of their recommended "core collection".
All compositions by Barry Harris except as indicated
"Magnificent" is the first official single from Rick Ross's third album Deeper Than Rap. It features John Legend and is produced by J.U.S.T.I.C.E. League. The song samples "Gotta Make It Up To You" by Angela Bofill and also contains an interpolation of "I'm The Magnificent" by Special Ed.
The official remix was made which features John Legend, Big Boi, Special Ed & Diddy.
The music video has cameo appearances from DJ Khaled, Birdman, Ace Hood, Triple C's and Special Ed. It was released on March 3, 2009 and it was directed by music video director Gil Green. It was filmed at Gulfstream Park Racetrack in Hallandale Beach, Florida.
BTK may refer to:
Birth Through Knowledge (aka BTK) was a Canadian hip-hop/rock band best known for their 1998 single "Peppyrock," the video for which was nominated for the 1998 MuchMusic Best Video Award. The band consisted of Lo-Ki (vocals), Stone Groove (vocals), DJ Spinz (turntables), Adam Carlo (bass),Sam Cino (drums,percussion) and Matt deMatteo (drums).
After signing onto the Tommyboy/Ignition label, BTK released one album "Birth Thru Knowledge" in 1998.
BTK first came to attention when their song "Corncob Pipe" was included on the sampler disc that Korn released alongside Follow the Leader. They were the first indie band to ever open the main-stage at Edgefest '97. In 1998, the band toured with the Beastie Boys and with Our Lady Peace. They appeared in the 1998 Summersault tour.
The band won the 1997 MuchMusic Best Independent Video Award for "Superchile." They were also nominated for a Juno Award in 1999 in the Best Alternative Album category, losing to Rufus Wainwright.
Bruton's tyrosine kinase (abbreviated Btk or BTK) also known as tyrosine-protein kinase BTK is an enzyme that in humans is encoded by the BTK gene. BTK is a kinase that plays a crucial role in B-cell development.
BTK plays a crucial role in B cell maturation as well as mast cell activation through the high-affinity IgE receptor.
Btk contains a PH domain that binds phosphatidylinositol (3,4,5)-trisphosphate (PIP3). PIP3 binding induces Btk to phosphorylate phospholipase C, which in turn hydrolyzes PIP2, a phosphatidylinositol, into two second messengers, inositol triphosphate (IP3) and diacylglycerol (DAG), which then go on to modulate the activity of downstream proteins during B-cell signalling.
Mutations in the BTK gene are implicated in the primary immunodeficiency disease X-linked agammaglobulinemia (Bruton's agammaglobulinemia). Patients with XLA have normal pre-B cell populations in their bone marrow but these cells fail to mature and enter the circulation. The Btk gene is located on the X chromosome. At least 400 mutations of the BTK gene have been identified.