Chrome

Chrome may refer to:

Materials

Computing

Music

Musicians

Albums and songs

Chromeč

Chromeč is a village and municipality (obec) in Šumperk District in the Olomouc Region of the Czech Republic. The municipality covers an area of 5.48 square kilometres (2.12 sq mi), and has a population of 580 (as at 3 July 2006). First note about the village comes from 1353 when the recent area was kept by multiple owners. Since 17th Century Chromeč was considered to be part of the Bludov Manor. The municipality became autonomous in 1990. The POW camp for British pilots was established in the Sokolovna during World War II.

Notable persons

Josef Drásal – the tallest Czech ever, suffering of gigantism. Drásal was famous member of circus in his time with notable performance for French emperor Napoleon III.

References

Coordinates: 49°56′N 16°54′E / 49.933°N 16.900°E / 49.933; 16.900

Chrome (XM)

Chrome was one of ten dance/electronica music satellite channels operated by Sirius XM Radio on channel 83 (and since November 2005 on DirecTV 861), and was one of five dance music channels offered by XM. The channel played classic disco and dance music from the 1970s through the 1980s and freestyle music which was popular from the mid-1980s to early 1990s. On November 12, 2008, the channel was eliminated from the XM lineup with the XM/Sirius merger, and no equivalent music was made available.

Chrome was one of the first channels offered by XM Satellite Radio at launch; the first song played was "Get Down Tonight" by KC & The Sunshine Band. The last song played was Donna Summer's "Last Dance." Among one of its jingling promos was "Where Disco DOESN'T Suck."

During November and December 2004, the channel was pre-empted for Special Xmas on the satellite service.

Sirius/XM announced on December 16, 2008 that the format hole will filled by The Strobe (a channel that was heard exclusively on Sirius before its removal on November 12, 2008), the name of the disco/classic dance channel, effective January 15, 2009.

Mad (village)

Mad (Hungarian: Nagymad, Hungarian pronunciation:[ˈnɒɟmɒd]) is a village and municipality in the Dunajská Streda District in the Trnava Region of south-west Slovakia.

Geography

The municipality lies at an altitude of 114 metres and covers an area of 7.714 km².

History

In the 9th century, the territory of Mad became part of the Kingdom of Hungary. The village was first recorded in 1254 as Mod, in 1260 as Nagmod. Until the end of World War I, it was part of Hungary and fell within the Dunaszerdahely district of Pozsony County. After the Austro-Hungarian army disintegrated in November 1918, Czechoslovakian troops occupied the area. After the Treaty of Trianon of 1920, the village became officially part of Czechoslovakia. In November 1938, the First Vienna Award granted the area to Hungary and it was held by Hungary until 1945. After Soviet occupation in 1945, Czechoslovakian administration returned and the village became officially part of Czechoslovakia in 1947.

Demography

In 1910, the village had 438, for the most part, Hungarian inhabitants. At the 2001 Census the recorded population of the village was 469 while an end-2008 estimate by the Statistical Office had the villages's population as 509. As of 2001, 95,74 per cent of its population was Hungarian while 4,05 per cent was Slovakian. Roman Catholicism is the majority religion of the village, its adherents numbering 69.51% of the total population.

Mad (Ne-Yo song)

"Mad" is a song by American pop/R&B singer Ne-Yo. It is the third single from his album Year of the Gentleman and was produced by Stargate and himself.

Music video

The video for the song was directed by Diane Martel. It premiered on AOL on November 25, 2008. The video, shot in black and white, presents a narrative wherein Ne-Yo argues with his girlfriend (played by Faune Chambers). After leaving, in an attempt to save a child from a car accident, someone is fatally hit. At the end of the video, it is revealed that the whole time it has been the ghost of Ne-Yo's character singing, and that it was he who was killed. The video to this song is Part 2 to his song Part of the List.

The music video appears to mirror the 1999 American thriller The Sixth Sense from M. Night Shyamalan, in which Bruce Willis plays a psychologist who is shot by an estranged patient of his. Based on how the film was shot and portrayed, Bruce Willis is shown in many situations as if he is there physically, when in actuality he was murdered by his patient, just as how Ne-Yo appears with his girlfriend, seeming to be there physically and that she is ignoring him due to their earlier argument, when he is actually dead.

Mad1

Mad1 is a non-essential protein in yeast which has a function in the spindle assembly checkpoint (SAC). This checkpoint monitors chromosome attachment to spindle microtubules and prevents cells from starting anaphase until the spindle is built up. The name Mad refers to the observation that mutant cells are mitotic arrest deficient (MAD) during microtubule depolymerization. Mad1 recruits the anaphase inhibitor Mad2 to unattached kinetochores and is essential for Mad2-Cdc20 complex formation in vivo but not in vitro. In vivo, Mad1 acts as a competitive inhibitor of the Mad2-Cdc20 complex. Mad1 is phosphorylated by Mps1 which then leads together with other activities to the formation of the mitotic checkpoint complex (MCC). Thereby it inhibits the activity of the anaphase-promoting complex/cyclosome (APC/C). Homolog’s of Mad1 are conserved in eukaryotes from yeast to mammals.

Introduction

In the early 90s, yeast genes were identified which mutations resulted in a defect in mitotic arrest in response to microtubule disassembly (mitotic arrest deficient genes - MAD genes). This cells showed during division no mitotic arrest in the presence of microtubule polymerization inhibitors and were therefore not able to delay cell division. The genes identified included the MAD1, MAD2 and MAD3 genes. They are conserved in all eukaryotes and are involved in a pathway that is active in prometaphase to prevent the premature separation of sister chromatids and constitute the so-called spindle assembly checkpoint(SAC). This checkpoint monitors the status of chromosome attachment to the mitotic spindle and inhibits the metaphase to anaphase transition by preventing the activation of the anaphase-promoting complex/cyclosome (APC/C), and thereby the degradation of cell cycle regulators. Mad1 is in this pathway accumulated at unattached kinetochores and acts as a sensor for unattached kinetochores in this machinery.