MOCS2
Molybdenum cofactor synthesis protein 2A and molybdenum cofactor synthesis protein 2B are a pair of proteins that in humans are encoded from the same MOCS2 gene. These two proteins dimerize to form molybdopterin synthase.
Function
Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from cyclic pyranopterin monophosphate (precursor Z) by the heterodimeric enzyme molybdopterin synthase.
Gene
The large and small subunits of molybdopterin synthase are both encoded from the MOCS2 gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.
The MOCS2 gene contains 7 exons. Exons 1 to 3 encode MOCS2A (the small subunit), and exons 3 to 7 encode MOCS2B (large subunit).
Podcasts:
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by Mxs
Hooray For Me
by: MxsI can see my teenage father standing straight on a
desolate corner,
in the shadow of tentacled towers by the red light of
America,
I imagine how his mother felt when she heard that her
husband was dying,
and that underground heroes of the tarmac
shooting smack were blowing up worlds
and Damned out loud,
he, can you tell me how does it feel?
yeah, tell me, can you imagine, for a second,
doing anything that you don't have to?
well that's what I'm accustomed to so hooray for me
when I slept with stony faces on the riverbank,
my angeldevil reveller shook me desperately in dying,
I don't exactly want to apologize for anything, and now
we're all mad and tangled in secret rooms with roman
candles,
on an endless graveyard train
yeah, tell me, can you imagine, for a second, doing
anything just 'cuz you want to?
well, that's just what I do so hooray for me
yeah, I was dreaming through the "howzlife", yawning,
car black, when she told me "mad and meaningless as
ever..",
and a song came on my radio like a cemetery rhyme,
for a million crying corpses in their tragedy of
respectable existence
oh, yeah, I'm not respectable, and never sensible,
I've been incredible so damned irascible