MME (psychedelic)
MME, or 2,4-dimethoxy-5-ethoxyamphetamine, is a lesser-known psychedelic drug. It is a dimethoxy-ethoxy analog of TMA-2. MME was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 40 mg, and the duration listed as 6–10 hours. Shulgin gives MME a ++ on the Shulgin Rating Scale. Very little data exists about the pharmacological properties, metabolism, and toxicity of MME.
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Madam
Madam /ˈmædəm/, or, as French, madame /ˈmædəm/ or mə-dam', is a polite form of address for women, often contracted to ma'am /ˈmæm/. The abbreviation is "Mme" and the plural is mesdames (abbreviated Mmes). The term was borrowed from the French madame (French pronunciation: [maˈdam]), which means "my lady".
Use as a form of address
In speaking, Madam is used in direct address when the lady's name is not known; for example: May I help you, madam? In the United States, "ma'am" is usually used, except in regions such as New England where particular ties to England still exist. Even then, "madam" tends to only be used when addressing the elderly, with "ma'am" being used for a younger woman. The male equivalent is "sir".
Formal protocol
After addressing her as "Your Majesty" once, it is correct to address the Queen of the United Kingdom as "Ma'am" for the remainder of a conversation.
In 2009 the European Parliament issued guidance on the use of gender-neutral language which discouraged the use of terms which indicate a woman's marital status.
MME
MME may stand for:
Neprilysin
Neprilysin (/ˌnɛprᵻˈlaɪsᵻn/ ), also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10), and common acute lymphoblastic leukemia antigen (CALLA) is an enzyme that in humans is encoded by the MME gene. Neprilysin is a zinc-dependent metalloprotease that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. It also degrades the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface.
Neprilysin is expressed in a wide variety of tissues and is particularly abundant in kidney. It is also a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.
Psychedelic
The psychedelic is a concept the name of which is derived from the Ancient Greek words psychē (ψυχή, "soul") and dēloun (δηλοῦν, "to make visible, to reveal"), translating to "mind-revealing".
Related phenomena include:
- Psychedelic rock, originating in the mid-1960s
- Psychedelic folk, originating in the late 1960s and early 1970s
- Psychedelic pop, which combines pop music with influences from psychedelic rock and psychedelic folk
- Psychedelic soul, which combines soul music with influences from psychedelic rock
- Psychedelic trance (also known as psytrance or simply psy), an electronic music style originating in the late 1990s
Psychedelic music
Psychedelic music (sometimes psychedelia) covers a range of popular music styles and genres influenced by psychedelic culture that attempted to replicate or enhance the psychedelic experiences of psychedelic drugs. It emerged during the mid-1960s among folk rock and blues rock bands in the United States and Britain.
Psychedelic bands often used new recording techniques and effects, drawing on non-Western sources such as the ragas and drones of Indian music. Psychedelic influences spread into folk, rock, and soul, creating the subgenres of psychedelic folk, psychedelic rock, psychedelic pop and psychedelic soul in the late 1960s before declining in the early 1970s. Psychedelic music bands expanded their musical horizons, and went on to create and influence many new musical genres including progressive rock, kosmische musik, electronic rock, jazz rock, heavy metal, glam rock, funk, electro and bubblegum pop. Psychedelic music was revived in a variety of forms of neopsychedelia from the 1980s, in psychedelic hip hop and re-emerged in electronic music in genres including acid house, trance music and new rave.
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