Histone-lysine N-methyltransferase 2D (KMT2D) previously known as myeloid/lymphoid or mixed-lineage leukemia protein 2 (MLL2) is an enzyme that in humans is encoded by the KMT2D gene. The gene is located on chromosome 12.This is a Trithorax-group protein.
This gene is also generally known as MLL4 in the literature. This nomenclature has caused much confusion in the data bases. Originally MLL2 was used to describe the sister gene of MLL1, which is also a trithorax-group histone methyltransferase.
The MLL1 gene was originally named MLL after myeloid/lymphoid or mixed-lineage leukemia cases. Its closest homologue is a very similar gene (not the gene described here), which is also called MLL2, but sometimes unfortunately called MLL4. The gene described here as MLL2 should properly be called MLL4 because along with its closely related homologue MLL3, it is closely related to a different Drosophila homologue of trithorax. The material included below refers to the trithorax group protein that is associated with MLL3 and a protein complex, not containing menin but including PTIP. It is listed as MLL2 but it should properly be called MLL4. It is now understood that its effect in lymphomagenesis is via the disruption of chromatin regulation.
Aha aha aha aha aha
Ohhhh all the boyfriend beware
Ehi baby what's up? What you doin' tonight?
Oh yeah I'm going down to the Whistle's Party
The man, leave your boyfriend home
and why don't you come with me
because It's the place that's gonna make you feel good
I don't wanna in not
but if you wanna come you just call me, ok?
Ciao baby
In the beginning
in this time to movin to the left and dancing to the
right
we shake our bodies at the discotek
but now is the time to just feel good
Welcome to the place that feels good
Welcome to the place that feels good
Welcome to the place that feels good
Welcome to the place that feels good
Walking down the street I'm thinking about you
I'm thinking all the times the times we're together
if you wanna come with me blow your whistle to the beat
here I am all alone waiting for you to phone
Blow your whistle
let me blow your whistle the whistle
let me blow your whistle the whistle the whistle
let me blow your whistle the whistle
let me blow your whistle the whistle
blow your whistle
Welcome to the place that feels good
Welcome to the place that feels good
Welcome to the place that feels good
Welcome to the place that feels good
I'm walking down the street I'm thinking about you
I'm thinking all the times the times we're together
if you wanna come with me blow your whistle to the beat
here I am all alone waiting for you to phone
Blow your whistle
let me blow your whistle the whistle
let me blow your whistle the whistle the whistle
let me blow your whistle the whistle
let me blow your whistle the whistle
blow your whistle
Blow your whistle
let me blow your whistle the whistle
let me blow your whistle the whistle the whistle
let me blow your whistle the whistle
let me blow your whistle the whistle