MIND MGMT
MIND MGMT is an ongoing American comic book series created by Matt Kindt and published through Dark Horse Comics with an expected run of 36 issues. The first issue was released on May 23, 2012 to good reviews, and received a second printing in April 2013. The series continued to receive positive coverage into its second year. A film version began preproduction in January 2013.
The story is about Meru, a true crime writer who searches for the truth behind a mysterious airline flight and discovers a secret government agency of super spies, espionage, and psychic abilities. Henry Lyme, the former top agent, has gone rogue and is working to dismantle the organization.
Publication history
Development
The idea for MIND MGMT came from the title, which one of Kindt's friends gave to him. He worked on the concept for over a year, and the plot was outlined in a twelve-page synopsis.
After partnering for one of Kindt's previous works, 3 Story: The Secret History of the Giant Man, Dark Horse Publisher Mike Richardson asked Kindt to pitch another book. Kindt sent the proposal for MIND MGMT and was happy when it was accepted because Dark Horse was "the only publisher able to pay me a living wage and also let me do exactly what I wanted no matter what." The series was initially approved for over 50 issues, but Kindt pruned away excess material and reduced the run to 36 issues. Despite the reduction in length, the final product is still almost identical to the original pitch. Diana Schutz, editor of 3 Story, was originally slated to work with Kindt again, but the project was handed to newly promoted editor Brendan Wright very early in production. Kindt described their input as "invaluable" and considers Wright to be a collaborator.
Mind
A mind /ˈmaɪnd/ is the set of cognitive faculties that enables consciousness, perception, thinking, judgement, and memory—a characteristic of humans, but which also may apply to other life forms.
A lengthy tradition of inquiries in philosophy, religion, psychology and cognitive science has sought to develop an understanding of what a mind is and what its distinguishing properties are. The main question regarding the nature of mind is its relation to the physical brain and nervous system – a question which is often framed as the mind–body problem, which considers whether mind is somehow separate from physical existence (dualism and idealism), or the mind is identical with the brain or some activity of the brain, deriving from and/or reducible to physical phenomena such as neuronal activity (physicalism). Another question concerns which types of beings are capable of having minds, for example whether mind is exclusive to humans, possessed also by some or all animals, by all living things, or whether mind can also be a property of some types of man-made machines.
Mind (charity)
Mind is a mental health charity in England and Wales. Founded in 1946 as the National Association for Mental Health (NAMH), it celebrated its 60th anniversary in 2006.
Mind offers information and advice to people with mental health problems and lobbies government and local authorities on their behalf. It also works to raise public awareness and understanding of issues relating to mental health. Since 1982, it has awarded an annual prize for "Book of the Year" having to do with mental health, in addition to three other prizes
Over 180 local Mind associations (independent, affiliated charities) provide services such as supported housing, floating support schemes, care homes, drop-in centres and self-help support groups. Local Mind associations are often very different in size, make up and character—it is a common misconception that they all work to the same policy and procedural framework. Mind is a national brand but all local associations are unique, although they do all sign up to certain shared aims and ethical guidelines.
Mind (song)
"Mind" was a single by Liverpool-based pop group The Farm, released as the first single off their second album Love See No Colour. It was released on 12 August 1991, having been produced by Graham "Suggs" McPherson of Madness. The single peaked at #31 on the UK Singles Chart.
Track listing
UK CD single
MGMT
MGMT is an American rock band formed in 2002 by Benjamin Goldwasser and Andrew VanWyngarden. After the release of their first album, the members of their live band, Matthew Asti, James Richardson and Will Berman, joined the core band in the studio. Formed at Wesleyan University and originally with Cantora Records, they signed with Columbia Records and Red Ink in 2006.
On October 5, 2007, Spin.com named MGMT "Artist of the Day." On November 14, 2007, Rolling Stone pegged MGMT as a top ten "Artist to Watch" in 2008. The band was named ninth in the BBC's Sound of 2008 Top Ten Poll. They were also named as Last.fm's most played new artist of 2008 in their Best of 2008 list.
MGMT's first album, Oracular Spectacular, debuted at No. 12 on the UK album chart, No. 13 after 34 weeks in the New Zealand RIANZ charts, number six on the Australian ARIA Charts, and hit number one on the Billboard Top Heatseekers chart. It has also been named the 18th best album of the 2000s by Rolling Stone magazine. It was named the best album of 2008 by NME. MGMT also appeared prominently in Australia's Triple J Hottest 100 2008, coming in 2nd with "Electric Feel", 5th with "Kids" and 18th with "Time to Pretend".
O-6-methylguanine-DNA methyltransferase
O6-alkylguanine DNA alkyltransferase (also known as AGT, MGMT or AGAT) is a protein that in humans is encoded by the O6-methylguanine DNA methyltransferase (MGMT) gene. O6-methylguanine DNA methyltransferase is crucial for genome stability. It repairs the naturally occurring mutagenic DNA lesion O6-methylguanine back to guanine and prevents mismatch and errors during DNA replication and transcription. Accordingly, loss of MGMT increases the carcinogenic risk in mice after exposure to alkylating agents. The two bacterial isozymes are Ada and Ogt.
Function and mechanism
Although alkylating mutagens preferentially modify the guanine base at the N7 position, O6-alkyl-guanine is a major carcinogenic lesion in DNA. This DNA adduct is removed by the repair protein O6-alkylguanine DNA alkyltransferase through an SN2 mechanism. This protein is not a true enzyme since it removes the alkyl group from the lesion in a stoichiometric reaction and the active enzyme is not regenerated after it is alkylated (referred to as suicide enzyme). The methyl-acceptor residue in the protein is a cysteine.
MGMT (album)
MGMT is the self-titled third studio album by American band MGMT released on September 17, 2013.
The album features a variety of unique visual elements to accompany and illuminate the new music via "The Optimizer", which provides listeners a simultaneously aural and optical listening experience featuring video and CGI work, and is available as part of an enhanced album package on all commercial formats.
History
On September 27, 2010, an interview article in Spin quoted them as saying that they will have less freedom on this album, claiming that Columbia was not happy with the reception of the band's second album, Congratulations. MGMT later denied these statements in an email to Pitchfork, who cited the article on their own site as a side note to a different story, stating that they were not "even close to starting the process of making a new album," that "label-relations are currently quite friendly," and finally telling readers "Don't believe everything that you read (even on Pitchfork.com)."
Podcasts:
