Intel's original MCS-51 family was developed using N-type metal-oxide-semiconductor (NMOS) technology like its predecessor Intel MCS-48, but later versions, identified by a letter C in their name (e.g., 80C51) used complementary metal–oxide–semiconductor (CMOS) technology and consume less power than their NMOS predecessors. This made them more suitable for battery-powered devices.
The family was continued in 1996 with the enhanced 8-bit MCS-151 and the 8/16/32-bit MCS-251 family of binary compatible microcontrollers. While Intel no longer manufactures the MCS-51, MCS-151 and MCS-251 family, enhanced binary compatible derivatives made by numerous vendors remain popular today. Some derivatives integrate a digital signal processor (DSP). Beyond these physical devices, several companies also offer MCS-51 derivatives as IP cores for use in field-programmable gate array (FPGA) or application-specific integrated circuit (ASIC) designs.