MCOPPB is a drug which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07 and much weaker activity at other opioid receptors. It has only moderate affinity for the mu opioid receptor, weak affinity for the kappa opioid receptor and negligible binding at the delta opioid receptor. In animal studies, MCOPPB produces potent anxiolytic effects, with no inhibition of memory or motor function, and only slight sedative side effects which do not appear until much higher doses than the effective anxiolytic dose range.
THERE'S TWO LITTLE MEN, WHO ARE FIGHTING A WAR
THEY CAN'T STOP IT NOW, IT'S BEEN TEN YEARS MAYBE MORE
ONE IS SMALL AND DEVIOUS, WITH HURT ON HIS MIND
THE OTHER BIG AND STRONG, WITH PRIDE ON HIS SIDE
ONE PLAYS DIRTY, HE'LL DO ANYTHING TO WIN
THE OTHER FENDS OFF THE ATTACKS, AGAIN AND AGAIN
THE BATTLEGROUNDS ARE SCARRED, TORN TO PIECES
RIPPED TO SHREDS
NEITHER CAN CLAIM VICTORY, TILL THE OTHER ONE IS DEAD
THERE'S TWO LITTLE MEN, WHO ARE KILLING A BOY
THEY'RE TREATING THE BOY, AS IF THE BOY WERE A TOY
EACH ONE HAS AN EAR, TO HAVE AND TO HOLD
THEIR GRIP IS TOO TIGHT, THEIR GRIP IS SO COLD
TWO LITTLE MEN - ONE BIG AND ONE SMALL
TWO LITTLE MEN - IN THE MIDDLE OF A WAR
TWO LITTLE MEN - AND I CAN'T SEE YOU
TWO LITTLE MEN - I'M USING AS A METAPHOR