MAL2 (gene)
Protein MAL2 is a protein that in humans is encoded by the MAL2 gene.
This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface.
Interactions
MAL2 (gene) has been shown to interact with TPD52.
References
Further reading
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.
Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term "having a gene" (e.g., "good genes," "hair colour gene") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.
Eugene (given name)
Eugene is a common (masculine) first name that comes from the Greek εὐγενής (eugenēs), "noble", literally "well-born", from εὖ (eu), "well" and γένος (genos), "race, stock, kin".Gene is a common shortened form. The feminine variant is Eugenia or Eugénie.
Male foreign-language variants include:
Notable people
Christianity
Military
Gene (novel)
Gene is a thriller novel by Stel Pavlou (born 1970), published in 2005 in England by Simon & Schuster. It is published in several languages with some title changes. The Italian edition has the title La Conspirazione del Minotauro (The Minotaur Conspiracy). The novel is about a fictional New York detective, James North, who in the process of hunting down a criminal, uncovers a genetics experiment to unlock past lives through genetic memory, therefore achieving a kind of immortality. In so doing North discovers his own origins, that of a soldier from the Trojan War who is reincarnated seven times through history, forced to confront his nemesis each time, all for the loss of his one true love.
Characters
Cyclades (born circa 1300 BC)
Incarnations of Cyclades
Athanatos (born circa 1500 BC)
Incarnations of Athanatos
Western Mallee
Western Mallee is an Interim Biogeographic Regionalisation for Australia (IBRA) subregion in southern Western Australia. It is a sparsely populated subregion with an area of about 47,000 square kilometres, roughly centred on the town of Newdegate. Largely cleared for intensive agriculture, it still retains patches of native vegetation, but these are under environmental stress from threats such as rising salinity, and are poorly managed.
Geography
Western Mallee is roughly defined as the western half of the Mallee biogeographic region. It has an area of 47,636 square kilometres, which is only lightly populated. The main towns are Hyden, Gnowangerup and Lake Grace; lesser towns include Kulin, Ongerup, Duggan, Newdegate, Lake King and Kondinin.
The subregion contains a number of ecologically important freshwater wetlands, including the Lake Bryde-East Lake Bryde wetlands, a DIWA Wetland of National Significance and habitat for a critically endangered threatened ecological community of shrub lake beds; the Lake Grace system of wetlands, also a DIWA Wetland of National Significance; and the Lake Cronin system.
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