Lofepramine
Lofepramine (brand name: Lomont (UK) Emdalen (ZA), Gamanil (IE, UK (discontinued)) & Tymelyt (discontinued)) is a third generationtricyclic antidepressant which was introduced in 1983 for the treatment of depressive disorders. Lofepramine is less sedating than, for instance, amitriptyline, and is safer in overdose than older tricyclics.
Indications
In the United Kingdom, Lofepramine is licensed for the treatment of depression which is its primary use in medicine.
Side effects
Common
- Constipation
- Dry Mouth
- Blurred Vision
- Sleepiness
Constipation
Dry Mouth
Blurred Vision
Sleepiness
Uncommon
- Central nervous system side-effects, particularly in the elderly, anxiety, dizziness, agitation, confusion, sleep disturbances, irritability, and paraesthesia
- Headache
- Nausea
- Palpitations
- Urinary Retention
- Sexual Dysfunction
Central nervous system side-effects, particularly in the elderly, anxiety, dizziness, agitation, confusion, sleep disturbances, irritability, and paraesthesia
Headache