Lemsip

Lemsip is a brand of cold and flu remedies in the United Kingdom, Republic of Ireland, Australia, and New Zealand. It is manufactured by Reckitt Benckiser. Their original and best-known product is a lemon-flavoured hot drink (hence the lem in Lemsip) containing 650 mg of paracetamol (an analgesic), and 10 mg phenylephrine hydrochloride (a decongestant) to help to relieve headache, fever, blocked nose, body aches and pains, and a sore throat. In 1995 The Lemsip Max platform was launched which included a Lemon, Blackcurrant and Breathe Easy hot drink flavours, and saw a variety of capsule products added to the range, including Lemsip Max Cold & Flu Capsules. The entire Lemsip Max range contains the maximum level of active ingredients allowed for general sales listing in the UK.

In 2007 Lemsip launched Lemsip Max All In One hot drinks in Lemon, Wild Berry & Hot Orange, and Breathe Easy flavours. In 2008 Lemsip launched a Liquid into the Lemsip Max All In One range. The range contains 200 mg of guaifenesin which helps to relieve "Chesty Cough", in addition to 1000 mg paracetamol and 12.2 mg of phenylephrine hydrochloride (12.18 mg of phenylephrine hydrochloride in Lemsip Max All In One Liquid) which aims to relieve headache, sore throat, fever, body aches and pains, and a blocked nose. The Lemsip range now contains capsules, tablets, liquids, and hot drink sachets.

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Laboratory for Experimental Medicine and Surgery in Primates

The Laboratory for Experimental Medicine and Surgery in Primates (LEMSIP) was a New York University research facility founded in 1965 by Edward Goldsmith and Jan Moor-Jankowski. The Tuxedo, New York-based outfit was a prominent vendor of primates and primate parts in the New York metropolitan area. These were used by area scientists for transplantation and virus research. The institute closed in 1998.

The facility was the subject of a documentary produced by National Geographic featuring Jane Goodall. The award-winning episode, Chimp Rescue, was broadcast in 1998, shortly after the closure of the facility. The documentary chronicled James Mahoney's efforts to save approximately one hundred primates prior to the closure of the facility.

One of the likely contributing factors to the demise of LEMSIP was the revision of the caging requirements prescribed by the USDA. The upgrades would have cost the university at least US$2 million. As a result, custody of several animals were passed on to the Coulston Foundation.

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SRC

Education

Sid Richardson College, residential college of Rice University campus, Houston, Texas, USA

Southern Regional College, a higher education college in Northern Ireland

Spoon River College, a community college in Illinois, USA

Students' representative council, of an institution

Sulaiman Al Rajhi Colleges, a university in Al Bukayriyah, Saudi Arabia

Music

SRC (band), a rock band from the late 1960s

SRC (album), the 1968 album by SRC

SRC (album), the 1968 album by SRC

SRC Records, an American record label

Science and technology

Src (gene), a family of proto-oncogenic tyrosine kinases

SRC, the human orthologue of the Src gene

SRC, the human orthologue of the Src gene

DEC Systems Research Center, a computer research laboratory

Saovang Rubber Company, a Vietnam tire company

Saskatchewan Research Council, a technology corporation

Science Research Council, later the Science and Engineering Research Council, a UK administrative agency

Semiconductor Research Corporation, a non-profit consortium founded in 1982

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Proto-oncogene tyrosine-protein kinase Src

Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src or simply c-Src , is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene. This protein phosphorylates specific tyrosine residues in other proteins. An elevated level of activity of c-Src tyrosine kinase is suggested to be linked to cancer progression by promoting other signals. c-Src includes an SH2 domain, an SH3 domain, and a tyrosine kinase domain.

c-Src stands for "cellular Src kinase" and should not be confused with "C-terminal Src kinase" (CSK) which is an enzyme which phosphorylates c-Src at its C-terminus and provides negative regulation of Src's enzymatic activity. c-Src is a widely studied member of non-receptor tyrosine kinases which are not associated with a cell-surface receptor.

Src (pronounced "sarc" as it is short for sarcoma) is a proto-oncogene encoding a tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus, for which they were awarded the 1989 Nobel Prize in Physiology or Medicine. It belongs to a family of non-receptor tyrosine kinases called Src family kinases.

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Nuclear receptor coactivator 2

The nuclear receptor coactivator 2 also known as NCoA-2 is a protein that in humans is encoded by the NCOA2 gene. NCoA-2 is also frequently called glucocorticoid receptor-interacting protein 1 (GRIP1), steroid receptor coactivator-2 (SRC-2), or transcriptional mediators/intermediary factor 2 (TIF2).

Function

NCoA-2 is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. NCOA2 is recruited to DNA promotion sites by ligand-activated nuclear receptors. NCOA2 in turn acetylates histones, which makes downstream DNA more accessible to transcription. Hence, NCOA2 assists nuclear receptors in the upregulation of DNA expression.

GRIP1 is a transcriptional co-activator of the glucocorticoid receptor and interferon regulatory factor 1 (IRF1).