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Agricultural University of Iceland
The Agricultural University of Iceland is an educational and research institution focusing on agricultural and environmental sciences, founded in 2005. The university's facilities are mainly located at Hvanneyri, near Borgarnes, Iceland but it also operates research stations in Reykjavík, Árnessýsla and Eyjafjarðarsýsla.
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External links
Coordinates: 64°33′40″N 21°46′11″W / 64.56111°N 21.76972°W / 64.56111; -21.76972
Panobinostat
Panobinostat (LBH-589, trade name Farydak) is a drug developed by Novartis for the treatment of various cancers. It is a hydroxamic acid and acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor).
On 23 February 2015 it received FDA accelerated approval for use in patients with multiple myeloma who had received at least 2 previous treatments, including bortezomib and an immunomodulatory agent." after clinical trials.
Clinical trials
As of August 2012, it is being tested against Hodgkin's Lymphoma, cutaneous T cell lymphoma (CTCL) and other types of malignant disease in Phase III clinical trials, against myelodysplastic syndromes, breast cancer and prostate cancer in Phase II trials, and against chronic myelomonocytic leukemia (CMML) in a Phase I trial.
As of 2014 Panobinostat is being used in a Phase I/II clinical trial that aims at curing AIDS in patients on highly active antiretroviral therapy (HAART). In this technique, panobinostat is used to drive the HIV DNA out of the patient's DNA, in the expectation that the patient's immune system in combination with HAART will destroy it.
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