Laurent Esso (born August 10, 1942) is a Cameroonian politician who has held a succession of key posts under President Paul Biya since 1988. He served in the government of Cameroon as Minister of Justice from 1996 to 2000, Minister of Public Health from 2000 to 2001, Minister of Defense from 2001 to 2004, and Minister of Foreign Affairs from 2004 to 2006. Subsequently Esso was Secretary-General of the Presidency, with the rank of Minister of State, from September 2006 to December 2011. He has again served as Minister of Justice since December 2011.
An ethnic Sawa, Esso was born at Douala. He was a magistrate and subsequently worked as Chancellor of the University of Yaoundé.
Esso left his post at the University of Yaoundé when President Paul Biya appointed him as Deputy Secretary-General of the Presidency on May 16, 1988. Considered a "reform-minded technocrat", Esso spent less than a year as Deputy Secretary-General of the Presidency before Biya instead appointed him as Director of the Civil Cabinet of the Presidency on April 13, 1989. Esso remained Director of the Civil Cabinet for seven years; he was then appointed as Minister of Justice in the government named on September 19, 1996. On March 18, 2000, he was moved from his position as Justice Minister to that of Minister of Public Health; after one year in the latter position, he was appointed as Minister-Delegate at the Presidency in charge of Defense on April 27, 2001. In the government named on December 8, 2004, he was instead appointed as Minister of Foreign Affairs, in which position he remained until he was appointed as Minister of State and Secretary-General of the Presidency on September 22, 2006.