Helm may refer to:
This is a list of Forgotten Realms deities. They are all deities that appear in the fictional Forgotten Realms campaign setting of the Dungeons & Dragons role-playing game.
The deities of other Dungeons & Dragons campaign settings, including those of the default (or "core") setting for the Dungeons & Dragons game, are not generally a part of Forgotten Realms. However, there is some overlap, especially among the deities of nonhuman races. Lolth, the principal deity of the drow in the Forgotten Realms, is specifically described as being the same deity as Lolth in other campaign settings. No mention is made as to whether other deities shared between Forgotten Realms and other campaign settings are intended to represent the same divine entity.
Deities are included in this list only when documented in a Forgotten Realms-specific source or otherwise clearly indicated as existing in the setting. For deities in the core setting, see List of deities of Dungeons & Dragons.
Helm is an English occupational surname of Anglo-Saxon origin, which was given to a herdsman. It was first found in Surrey, England. Notable people with this name include:
LAF may refer to:
This is a list of craters on Mars. There are hundreds of thousands of impact crater on Mars, but only some of them have names. This list here only contains named Martian craters starting with the letter H – N (see also lists for A – G and O – Z).
Large Martian craters (greater than 60 km in diameter) are named after famous scientists and science fiction authors; smaller ones (less than 60 km in diameter) get their names from towns on Earth. Craters cannot be named for living people, and small crater names are not intended to be commemorative - that is, a small crater isn't actually named after a specific town on Earth, but rather its name comes at random from a pool of terrestrial place names, with some exceptions made for craters near landing sites. Latitude and longitude are given as planetographic coordinates with west longitude.
Vildagliptin (previously LAF237, trade names Galvus, Zomelis,) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.
Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus.
Vildagliptin is a unique molecule with dual nature as it manages the glucagon levels in hypoglycemia as well as hyperglycemia.
The EMEA has also approved a new oral treatment released by Novartis, called Eucreas, a combination of vildagliptin and metformin.
Adverse effects observed in clinical trials include nausea, hypoglycemia, tremor, headache and dizziness. Rare cases of hepatoxicity have been reported.