LILRA3
Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILR-A3) also known as CD85 antigen-like family member E (CD85e), immunoglobulin-like transcript 6 (ILT-6), and leukocyte immunoglobulin-like receptor 4 (LIR-4) is a protein that in humans is encoded by the LILRA3 gene located within the eukocyte receptor complex on chromosome 19q13.4. Unlike many of its family, LILRA3 lacks a transmembrane domain. The function of LILRA3 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the LILRA3 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.
Like the closely related LILRA1, LILRA3 binds to both normal and 'unfolded' free heavy chains of HLA class I, with a preference for free heavy chains of HLA-C alleles
Podcasts:
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by Lola Ray
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by L8r
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by L8r
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by L8r
Automatic Girl
by: Lola RayShrink wrap your kiss in plastic love
Make my mind up when you return
I don't know what has happened to me these days
But it feels like love in the strangest ways
How much have you learned uh-oh
How much have yo-ou learned u-uh-oh
Don't fear cause when you return I'll be here
Waiting by your side, it doesn't matter dear
This is end of the world so it seems
I've got automatic love for automatic girl
This is the world of the end that I see
I've got automatic guns for automatic boys
Automatic toys for automatic girls
Everything keeps the right melody
I've got a couple of killing machines
(Automatic girl, automatic girl)
Lick my lips just to hear the sound
Trash my room when you're not around
I don't know what has happened to me these days
But it feels like love in the strangest ways
How much have we learned uh-oh
How much have we-e learned u-uh-oh
Don't fear cause when you return I'll be here
Waiting by your side, it doesn't matter dear
This is end of the world so it seems
I've got automatic love for automatic girl
This is the world of the end that I see
I've got automatic guns for automatic boys
Automatic toys for automatic girls
Everything keeps the right melody
I've got a couple of killing machines
I have...
(Automatic girls, automatic girls, automatic girl.... automatic!)
This is the end
This is the end
This is the end of the world so it seems
I've got automatic love for automatic girl
This is the world of the end that I see
I've got automatic guns for automatic boys
Automatic toys for automatic girls
Everything keeps the right melody
We've got a couple of killing machines
Automatic guns for automatic boys
Automatic toys for automatic girls
Everything keeps the right melody
Gotta a couple of killing machines
Couple of killin machines