Low-density lipoprotein

Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins. These groups, from least dense to most dense, are chylomicrons, very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein and high-density lipoprotein (HDL), all of which are far smaller than human cells.

Lipoproteins transfer fats around the body in the extracellular fluid, can be sampled from blood and allow fats to be taken up by the cells of the body by receptor-mediated endocytosis. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. They are typically composed of 80-100 proteins/particle (organized by a single apolipoprotein B for LDL and the larger particles). A single LDL particle is about 220-275 angstroms in diameter typically transporting 3,000 to 6,000 fat molecules/particle, varying in size according to the number and mix of fat molecules contained within. The fats carried include cholesterol, phospholipids, and triglycerides; amounts of each vary considerably.

LDL (disambiguation)

LDL is a low-density lipoprotein, one of the five major groups of lipoproteins.

LDL or LdL may also refer to:

  • Learning by teaching (German: Lernen durch Lehren, LdL), a method that allows students to learn by teaching lessons or parts of lessons
  • Loudness discomfort level, a measure of the volume where an individual starts feeling uncomfortable or feeling pain. It can be reduced in hyperacusis or recruitment.
  • LDL decomposition, Cholesky decomposition in linear algebra
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    Latest News for: ldl

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    Dr. Roizen: Use coffee filters to reduce your lousy LDL cholesterol

    Telegraph Herald 21 Apr 2025
    Grabbing a cup of coffee at work is a time-honored tradition — to boost your ability to concentrate on tasks at hand and to socialize for a couple of minutes with colleagues. In fact, one survey found that two-thirds of ... .
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    Dr. Roizen: Breakthrough in slashing elevated LDL cholesterol to save lives

    Telegraph Herald 16 Apr 2025
    More than 92 million Americans take statins, according to the Cleveland Clinic, and you can bet all of them are hoping that will protect them from having what doctors like to call “an adverse cardiovascular event” (aka heart attack, stroke, ... .
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    Lowering LDL 'bad' cholesterol can reduce dementia risk: Study

    India Today 02 Apr 2025
    Lowering LDL bad cholesterol can reduce dementia risk Study ... .
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    Is coffee from the office machine raising your LDL cholesterol? Here\u2019s the safest way to drink the brew

    Indian Express 01 Apr 2025
    Swedish researchers test machines, find plaque-forming compounds in insufficiently filtered coffee .
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    Can amla bust LDL cholesterol? Here\u2019s how much you should have daily

    Indian Express 31 Mar 2025
    Eating fresh amla is the most effective way to get its full spectrum of nutrients .
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    AZD0780, a novel oral PCSK9 inhibitor, demonstrated significant LDL cholesterol (LDL-C) reduction in PURSUIT Phase IIb trial (AstraZeneca Pharmaceuticals LP)

    Public Technologies 31 Mar 2025
    At 12 weeks, AZD0780 30mg taken once-daily (when added to the standard-of-care statin therapy and administered without any fasting or food restrictions) led to a 50.7% reduction in LDL-C [95% CI.
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