CD98
CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1). LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine) amino acids. LAT is highly expressed in brain capillaries (which form the blood–brain barrier) relative to other tissues.
A functional LAT1 transporter is composed of two proteins encoded by two distinct genes:
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Podcasts:
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by Loaded
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by Loaded
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by Loaded
King Of Downtown
by: LoadedYou're the king of downtown and
Nothing left to say
Cause you bled all believers then you
Washed it away
You're the king of downtown
And your jesters have stayed
But you've got nothin' comin'
Cause you got nothing left to say
Cause you're down
Chorus:
Can you take it? Gonna feel alright? Do you feel allright?
All's left forsaken and
You go back to Idaho cause
You're mommy is waiting
You've got nothing left to show
Can you feel it? Can you feel alright? Does it feel?
Can you take it? Can you take it down? Does it feel?
They had you to believe in
But you went away
Did you give them time?
It's good you went away
Gonna take it? Gonna take it down? Gonna feel