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Releasing the Brakes: The Role of Immune Checkpoint Inhibitors in Cancer Therapy

The Scientist 13 Mar 2025
The CTLA-4 and PD-1 checkpoints block co-stimulatory activation signaling, and immune checkpoint inhibitors (ICIs) such as anti-CTLA-4, anti-PD-1, and anti-PD-L1 therapies enable it ... PD-L1 protein expression.
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