KLK6

Kallikrein-6 is a protein that in humans is encoded by the KLK6 gene.

Function

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

References

Further reading

External links

  • The MEROPS online database for peptidases and their inhibitors: S01.236
  • KLK9

    Kallikrein-related peptidase 9 also known as KLK9 is an enzyme which in humans is encoded by the KLK9 gene.

    Function

    KLK9 belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. KLK9 is primarily expressed in thymus, testis, spinal cord, cerebellum, trachea, mammary gland, prostate, brain, salivary gland, ovary, and skin.

    Clinical significance

    KLK9 is under steroid hormone regulation in ovarian and breast cancer cell lines and is a potential prognostic marker for early-stage ovarian and breast cancer patients.

    References

    Further reading

    External links

  • The MEROPS online database for peptidases and their inhibitors: S01.307
  • KLK10

    Kallikrein-10 is a protein that in humans is encoded by the KLK10 gene.

    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

    References

    Further reading

    External links

  • The MEROPS online database for peptidases and their inhibitors: S01.246
  • Podcasts:

    PLAYLIST TIME:

    Learn About It

    by: Click

    Chorus-
    Understand this shit nigga learn about it
    Ay-thing a nigga spit need to know about it
    Understand this shit nigga learn about it
    Ay-thing a nigga spit nigga know about it
    Soak it up boy, ya know, ya know,
    ya know, ya know, ya know
    (E-40)
    Smebbin down the street in my 7-0
    Bumpin the beat sittin on gold tippity toes
    Went to the track to buy me some hemp
    Some old nigga yells out "40 you's a pimp"
    I said "Playboy understand my strategy
    Got to know a little somethin this dope game
    fall off into this catergory"
    I'm from that real live shit fuck hannabera
    I'm from the eighty four eighty fin era
    (B-Legit)
    I like to sake ‘em up rattle
    Baby got sattle
    If the nigga had a sack could I fuck with that
    Got to blowin' up her head with the chitter chatter
    I'm out the roof of my coup spittin game at her
    I likes to fuck and get up and get on
    I'm eatin' steak on the bone
    And steady stuffin dick in her dome
    I'm on the phone in my hot tube
    Gettin' my back rubbed on
    About to fall deep in the zone
    Let a nigga kick back and put ten to the ceiling
    Got my face in the pillow cuz I'm lovin the feelin
    Ain't nothin like nuttin' in her jaw
    So damn raw, Nipples pokin' out the bra
    (40)
    Man in the town I see
    Undertakers, Captain Savers, Cape crusaders, A P.H.er
    Plays in the game gettin' ratted on
    A ba A bitches in the game gettin over on
    Never tell a bitch all your buisness
    Cuz one day she might be an eye witness
    These are the things you need to know man
    This shit I'm spittin'
    Niggas don't understand
    Chorus
    (B-legit)
    Fools want to come up but ain't paid dues
    Want to hang around a player lookin' for clues
    Well in my younger days I did dirt
    Put in work, I used to but ki's from Kirk
    And nigga don't think that I wasn't the man
    Out there jiggin doin' all that I can
    But now in 95 I done flipped the scrip
    Hopin' muthafuckas understand this shit
    (40)
    We used to local till we signed with Jive
    40 numnum went nation wide
    Who would ever thought that Earl,Earl
    On the pitchers mound with the curl -Would be
    One of the biggest things to that ever came out the V
    Since Michael Copper and confunction barely graduatin Hogan High School
    Drunken, Hillside representitive, sky unlimited, game's unlimited
    Magazine street pioneer Ex D boy ask my cousin Troy
    Chorus
    Man, 40 would you rain on me man, Sprinkle me man
    Hey, would you tie my shoes lace me up or somethin
    Man I need to be sprinkled man Ay
    Understand this shit, nigga know about it,
    Know about it
    Kind of like when the drought about to hit you need to know about it
    You gotta done lived this shit to know about it
    Yeah, check game - a fool got at me the other day, Right?
    Rit.
    "Hey, hey B, How y'all niggas be comin with that ol' wild shit?"
    Huh?
    I say check game playboy, I'm from the 84 - eighty fin era
    Eighty fin era
    Where we done did that shit, know about that shit
    Know about that shit
    Spit that shit
    And it don't quit
    And it won't quit
    And it won't stop
    And it don't stop
    Fuck a hoe
    Fuck a bitch




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