| Kissing | |
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 Kissing
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Location of Kissing within Aichach-Friedberg district
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| Coordinates | 48°18′N 10°59′E / 48.3°N 10.98333°ECoordinates: 48°18′N 10°59′E / 48.3°N 10.98333°E |
| Administration | |
| Country | Germany |
| State | Bavaria |
| Admin. region | Swabia |
| District | Aichach-Friedberg |
| Mayor | Manfred Wolf (SPD) |
| Basic statistics | |
| Area | 23.12 km2 (8.93 sq mi) |
| Elevation | 523 m (1716 ft) |
| Population | 11,251 (31 December 2010)[1] |
| - Density | 487 /km2 (1,260 /sq mi) |
| Other information | |
| Time zone | CET/CEST (UTC+1/+2) |
| Licence plate | AIC |
| Postal code | 86438 |
| Area code | 08233 |
| Website | www.kissing.de |
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This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (May 2009) |
Kissing is a municipality in the Aichach-Friedberg district, in Bavaria, Germany. It is located just 10 km south of Augsburg and has about 11,200 inhabitants (2007).
Kissing was first mentioned in a document in 1050 AD as Chissingin, it was a minor regional centre of rule and jurisdiction called a Hofmark (German article). In even earlier times, around 500, there was a thing hill nearby, which was later swept away by the floods of the river Lech.
The surname Kissinger (as in Henry Kissinger) means inhabitant of Bad Kissingen.
See also [link]
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References [link]
- ^ "Fortschreibung des Bevölkerungsstandes" (in German). Bayerisches Landesamt für Statistik und Datenverarbeitung. 31 December 2010. https://www.statistikdaten.bayern.de/genesis/online?language=de&sequenz=tabelleErgebnis&selectionname=12411-009r&sachmerkmal=QUASTI&sachschluessel=SQUART04&startjahr=2010&endjahr=2010.
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https://wn.com/Kissing,_Bavaria
Lyn
Lyn or LYN may refer to:
A surname, variant of Lynn
In television and film:
In biochemistry:
Inanimate entities:
In other fields:
LYN
Tyrosine-protein kinase Lyn is a protein that in humans is encoded in humans by the LYN gene.
Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. In various hematopoietic cells, Lyn has emerged as a key enzyme involved in the regulation of cell activation. In these cells, a small amount of LYN is associated with cell surface receptor proteins, including the B cell antigen receptor (BCR),CD40, or CD19. The abbreviation Lyn is derived from Lck/Yes novel tyrosine kinase, Lck and Yes also being members of the Src kinase family.
Function
Lyn has been described to have an inhibitory role in myeloid lineage proliferation. Following engagement of the B cell receptors, Lyn undergoes rapid phosphorylation and activation. LYN activation triggers a cascade of signaling events mediated by Lyn phosphorylation of tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the receptor proteins, and subsequent recruitment and activation of other kinases including Syk, phosholipase Cγ2 (PLCγ2) and phosphatidyl inositol-3 kinase. These kinases provide activation signals, which play critical roles in proliferation, Ca2+ mobilization and cell differentiation. Lyn plays an essential role in the transmission of inhibitory signals through phosphorylation of tyrosine residues within the immunoreceptor tyrosine-based inhibitory motifs (ITIM) in regulatory proteins such as CD22, PIR-B and FCγRIIb1. Their ITIM phosphorylation subsequently leads to recruitment and activation of phosphatases such as SHIP-1 and SHP-1, which further downmodulate signaling pathways, attenuate cell activation and can mediate tolerance. In B cells, Lyn sets the threshold of cell signaling and maintains the balance between activation and inhibition. Lyn thus functions as a rheostat that modulates signaling rather than as a binary on-off switch.
Lyn (singer)
Lee Se-jin (born on Seoul, South Korea on 9 November 1981) is a South Korean R&B singer known professionally as Lyn. She has released ten full albums to date.
Biography
Lyn was born in Seoul, South Korea on 9 November 1981. She graduated from Seoul High School and attended University of Seoul.
Career
Lyn was first scouted by an agency because of her voice and from there, she first made her debut under her real name, Lee Se-jin, and released an album. The album sold poorly and was barely known. Lyn then took some time off to train vocally. She made a comeback in 2002 under the name Lyn with her supposedly first album Have You Ever Have A Broken Heart?. It was very successful and was able to shoot her up to one of the top R&B female solo singer of the year. After a surprise two years hiatus, Lyn released her second album Can U See The Bright. The album was very successful, surpassing her previous album with her popular single, "사랑했잖아" (Used To Love). Due to its popularity, the song was eventually covered on another successful singer Lee Seung-gi's album, released in late 2006. Lyn released her third album, The Pride of the Morning, on March 7, 2007, and sold 15,358 copies in that month, placing second in the Music Industry Association of Korea's monthly chart. Again, it was a success and was once again reclaim her title as one of the best R&B female singer. Overall her album sold 25,171 copies. Lyn then released more albums afterwards, and did not become very successful, but in 2009 she made a comeback with her 5th album called 'Let Go, Let In, It's a New Day'. In early 2012, she released her 7th album title 'Love Fiction'.
