KLC1
Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene.
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.
Podcasts:
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by Kelly Keagy
Everything I Need In A Woman
by: Kelly KeagyThis is a story
As old as time
About losing love
And finding love again.
Givin’ up on everything
losing faith that tryin
Would bring me home,
Take me home once again.
Never stop believin’ in a
Power strong enough
To take me back
And make me feel
The magic of a touch.
You’re everything I need in a woman
You’re what made me believe in love again
You’re where I want to be with a woman
But it’s gonna take a real woman
To make me believe in love again
I wanna believe in love again.
Without even knowin’,
You can read my mind
You sang right through
The hardness of my heart.
Could it be that you’ve been through
Everything I’ve been through?
And now we’ve both found our way in the dark
I was always reachin’
But it was just beyond my touch
I had everything I wanted
But it was never quite enough
You’re everything I need in a woman
You’re what made me believe in love again
You’re where I want to be with a woman
But it’s gonna take a real woman
To make me believe in love again
I wanna believe in love again.
Now gone are the dark days that kept me from the night
Now I know the way my life’s supposed to be
When we’re apart you’re always in my heart
There’s a part of you that’s still a part of me
You’re everything I need in a woman
You’re what made me believe in love
You’re everything I need in a woman
You’re what made me believe in love
You’re everything that’s meant to be in a woman
You’re everything I need in a woman
But it’s gonna take a real woman
To make me believe in love again