KCNJ3

Potassium inwardly-rectifying channel, subfamily J, member 3, also known as KCNJ3 or Kir3.1, is a human gene.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a hetero-tetrameric pore-forming complex.

Interactions

KCNJ3 has been shown to interact with KCNJ5.

See also

  • G protein-coupled inwardly-rectifying potassium channel
  • Inward-rectifier potassium ion channel
  • References

    Further reading

    External links

  • KCNJ3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
  • This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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