Kir2.1
The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene.
Clinical significance
A defect in this gene is associated with Andersen-Tawil syndrome.
A mutation in the KCNJ2 gene has also been shown to cause short QT syndrome.
In research
A trafficking sequence from Kir2.1 has been added to halorhodopsin to improve its membrane localization. The resulting protein eNpHR3.0 is used in optogenetic research to inhibit neurons with light.
Interactions
Kir2.1 has been shown to interact with:
References
Further reading
External links
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Kir2.1
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