Jean Pieters (born 5 January 1962 in Heerlen) is a Dutch biochemist and Professor at the Biozentrum of the University of Basel, Switzerland.
Jean Pieters studied biochemistry and microbiology at the University of Leuven in Belgium. After completing his doctorate at Maastricht University, the Netherlands, he joined the European Molecular Biology Laboratory (EMBL) in Heidelberg in 1989 as a postdoctoral fellow. From 1992 until 1995 Jean Pieters researched at the Netherlands Cancer Institute in Amsterdam as a junior group leader. In 1996 he was recruited to the Basel Institute for Immunology and in 2002 appointed to the Biozentrum at the University of Basel where he since teaches and continues his research as Professor of Biochemistry.
Jean Pieters investigates the role of coronin proteins in activating cellular signal transduction processes. Coronin proteins are widely distributed in the eukaryotic kingdom and conserved from yeast to man. One of the most conserved members of this protein family, mammalian coronin 1, was originally discovered in his laboratory as a host factor responsible for the intracellular survival of pathogenic mycobacteria (Ferrari 1999). Subsequent work from his laboratory showed that coronin proteins regulate diverse physiologic processes including T cell homeostasis (Mueller 2008), learning and memory (Jayachandran 2014) and development (Vinet 2014). Recent work from his and other laboratories suggests that mutations in coronin proteins may underlie immune-related and cognitive disorders in humans, implicating coronin proteins in important physiological pathways.
Pieters is a Dutch surname, equivalent to Peters. It can refer to:
Jean may refer to:
Jean, also known as the Vitagraph Dog (190? – 1916), was a female Collie that performed leading roles in early silent films. She was the first canine star in the United States having been preceded by the first, Blair, Cecil Hepworth's dog, in England. She however was the first canine to have her name in the title of her films. She was a precursor to other famous U.S. dog actors like Teddy, the Sennett Dog, Pete the Pup, Strongheart and Rin Tin Tin.
Around 1908, Maine resident and writer Laurence Trimble sold an animal story to a New York magazine. It paved the way for him to visit Vitagraph Studios with his dog, Jean, to do a story on film making. Trimble and his pet just happened to be on the set at a time when the company needed a dog to play a scene opposite Florence Turner. As a result, dog and master were asked to stay and both became members of the Vitagraph stock company.
"Jean was equal in popularity to Vitagraph's human stars, Florence Turner and Maurice Costello," wrote film historian Anthony Slide. Jean was soon known as the Vitagraph Dog, starring in her own films, all directed by Trimble. One-reelers and two-reelers with titles such as Jean and the Calico Doll, Jean and the Waif and Jean Goes Fishing were made by Trimble as their troupe filmed along the coastline in his native Maine.
Breath of Fire II (Japanese: ブレス オブ ファイアII 使命の子, Hepburn: Buresu obu Faia Tsū: Shimei no Ko, Breath of Fire II: The Destined Child) is a role-playing video game developed and published by Capcom. First released in 1994, the game was licensed to Laguna for European release in 1996. It is the second entry in the Breath of Fire series. It was later ported to Game Boy Advance and re-released worldwide. The game has been rated by the ESRB for release on Wii's Virtual Console and was released in North America on August 27, 2007. Nintendo of Europe's website mistakenly announced it for release on July 27, 2007, but it was in fact released two weeks later, on August 10, 2007.
Unlike later installments in the series, Breath of Fire II is a direct sequel to Breath of Fire. Set 500 years after the original game, the story centers on an orphan named Ryu Bateson, whose family vanished mysteriously long ago. After his friend is falsely accused of a crime, Ryu embarks on a journey to clear his name.