Factor X
Factor X, also known by the eponym Stuart–Prower factor, is an enzyme (EC 3.4.21.6) of the coagulation cascade. It is a serine endopeptidase (protease group S1, PA clan).
Physiology
Factor X is synthesized in the liver and requires vitamin K for its synthesis.
Factor X is activated, by hydrolysis, into factor Xa by both factor IX (with its cofactor, factor VIII in a complex known as intrinsic Xase) and factor VII with its cofactor, tissue factor (a complex known as extrinsic Xase). It is therefore the first member of the final common pathway or thrombin pathway.
It acts by cleaving prothrombin in two places (an arg-thr and then an arg-ile bond), which yields the active thrombin. This process is optimized when factor Xa is complexed with activated co-factor V in the prothrombinase complex.
Factor Xa is inactivated by protein Z-dependent protease inhibitor (ZPI), a serine protease inhibitor (serpin). The affinity of this protein for factor Xa is increased 1000-fold by the presence of protein Z, while it does not require protein Z for inactivation of factor XI. Defects in protein Z lead to increased factor Xa activity and a propensity for thrombosis.
Factor X (disambiguation)
Factor X, also known as Stuart-Prower factor or as thrombokinase, is an enzyme.
Factor X may also refer to:
See also
El Factor X
El Factor X is the Colombian television music competition to find new singing talent. It is the based on the original British competition The X Factor, created by Simon Cowell. It is the first version produced in Latin America.
The show started screening in September 2005. The judges were Marbelle, singer Juan Carlos Coronel, and José Gaviria, a producer who has worked with stars like Carlos Santana. The winner was Julio César Meza. A second series followed in 2006 won by Francisco Villarreal and a third one, after a 2-year hiatus, in 2009 won by the duo Siam. The show will come back in 2012 for a fourth season, again after a hiatus of another 2 years.
All seasons and versions of the show have been hosted by the Colombian TV host and top model Andrea Serna, produced by Teleset and broadcast on RCN TV.
The show had two spin-offs. One was the one-year series El Factor X: Batalla de las Estrellas (meaning the Battle of the Stars). It was broadcast in 2006 and was won by Luz Amparo Álvarez.
Podcasts:
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Entretien avec un empire
by: Factor XJango Jack
Baby s'il te plait ?coute ce couplet
Prend le comme une fleur ma musique aux p?tales dor?es
Assis sur un banc dans mon quartier
Je pense ? toi, je n'sais plus quoi faire
Putain c'est compliqu? quand on s'implique
Je n'sais plus quoi faire
J'pleure comme un naze, parle comme un lova lover
Je n'sais plus quoi faire
Refrain (x2)
J'entends mon coeur qui fait des boom boom
Dans mon hall ca resonne ca fait boom boom
J'ai jamais connu ca jamais boom boom
S.o.s mayday mayday boom boom
Mais baby s'il te plait sort de mes pensees
Personne ne sait comment j'tai kiffer
Ma reputation de chauds gars ?tait usurp?e
Et face a toi je n'sais plus quoi faire
J'suis tomb? lentement comme dans un gouffre rempli de sentiments
Je n'sais plus quoi faire
C'est mon destin du 9.1 au 9.2 j'suis love d'elle
Je n'sais plus quoi faire
Refrain
Proche du coma mon coeur j'te donne comme un gage
Baby de mon amour qui est hors du commun
J'suis despee j'parle de mes sentiments
Personne pourra me dire comment ton coeur me blesse
Princesse dis moi comment fait-on
Lorsque que ton coeur te frappe comme un gars qui te boxe
parce que personne ne dors j'crie sous la douleur
Je t'aime comme un f.o.u, la fl?che ma eue
Ca bounce come on bounce come on
Veux-tu que l'on m'arr?te si je t'aime comme un gamin
Ca boom boom dans mon body
C'est des balles doom doom que l'on entends l.o.v.e
M?me sur de cendres incandescents je marcherai jusqu'? ta porte
M?me si c'est cent hommes que je dois vaincre ? la force de mes mains
J'entend mon coeur qui fait...
Refrain (x2)