Air Inter Flight 148

Air Inter Flight 148 was a scheduled airline flight on 20 January 1992 that crashed in the Vosges Mountains, near Mont Sainte-Odile, while circling to land at Strasbourg Airport. Of 96 people on board, nine survived.

Accident

Flight 148, commanded by Captain Christian Hecquet and First Officer Joël Cherubin, departed Satolas Airport (now known as Lyon-Saint Exupéry Airport) in Lyon, France. While being vectored for a VOR/DME approach to runway 05 at Strasbourg, it crashed at 19:20:33 CET (18:20:33 UTC) in the mountains at an altitude of 2,620 feet (800 m).

The pilots had no warning of the imminent impact because Air Inter had not equipped its aircraft with a ground proximity warning system (GPWS). It is speculated that this was because Air Inter – facing ferocious competition from France's TGV high-speed trains – may have encouraged its pilots to fly fast at low level (up to 350 knots below 10,000 feet, while other airlines generally do not exceed 250 knots), and GPWS systems gave too many nuisance warnings.

Givinostat

Givinostat (INN) or gavinostat (originally ITF2357) is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride.

Givinostat is in numerous phase II clinical trials (including for relapsed leukemias and myelomas), and has been granted orphan drug designation in the European Union for the treatment of systemic juvenile idiopathic arthritis and polycythaemia vera.

ITF2357 was discovered at Italfarmaco of Milan, Italy. It was patented in 1997 and first described in the scientific literature in 2005.

Adverse effects

In clinical trials of givinostat as a salvage therapy for advanced Hodgkin's lymphoma, the most common adverse reactions were fatigue (seen in 50% of participants), mild diarrhea or abdominal pain (40% of participants), moderate thrombocytopenia (decreased platelet counts, seen in one third of patients), and mild leukopenia (a decrease in white blood cell levels, seen in 30% of patients). One-fifth of patients experienced prolongation of the QT interval, a measure of electrical conduction in the heart, severe enough to warrant temporary suspension of treatment.

ITF-1

ITF-1, also known as Yui was an amateur radio cubesat built by Tsukuba University of Japan.

It has a size of 100x100x100mm (without antenna) and build around a standard 1U cubesat bus. The primary satellite purpose is the raising awareness of space by providing easily decoded signal to amateur radio receivers. ITF-1's mission was unsuccessful; no signal from the spacecraft was ever received and it reentered to Earth atmosphere on 29 June 2014.

See also

  • List of CubeSats
  • References

    External links

  • Project page
  • ITF-1 page on Amsat - amateur radio community
  • Orbital data of ITF-1
  • Gunters space page on ITF-1

  • Podcasts:

    PLAYLIST TIME:

    Latest News for: itf

    Edit

    Chile to host ITF Juniors

    Inside The Games 20 Apr 2025
    "We are very pleased that the Billie Jean King Cup Juniors and Davis Cup Juniors Finals are returning to Santiago this year," ITF President David Haggerty said in the organisation’s press release.
    Edit

    Nadir wins ITF Leg II

    The News International 19 Apr 2025
    Representational image of a tennis racket and ball ... Nadir Mirza emerged the winner of the boys’ singles in the ITF Pakistan World Juniors Tennis Championship 2025 Leg-II, as his opponent Takaya Ishi (Japan) was unwell to play Saturday’s final ... .
    Edit

    Nadir Mirza makes ITF Juniors final

    Dawn 18 Apr 2025
    ISLAMABAD. Local player Nadir Mirza set up a ITF World Juniors Tennis Championship final date with Japan’s Takaya Ishi after beating compatriot Abubakar Talha 7-5, 6-1 in the boys’ singles semi-final here at the PTF Tennis Complex on Thursday ... .
    Edit

    Young Tennis Players Impress At ITF J30 Tournament

    The Botswana Gazette 16 Apr 2025
    Emerging stars signal bright future for local tennis TLOTLO KEBINAKGABO ...
    Edit

    ITF welcomes MLC amendments and highlights role of seafarers

    SAFETY4SEA 16 Apr 2025
    Seafarers’ Group spokesperson and ITF Seafarers’ Section Vice Chair, Mark Dickinson, said ... … commented ITF Seafarers’ Section Coordinator, Fabrizio Barcellona. .
    Edit

    Young players to take part in ITF J30 Bình Dương for U18s

    Vietnam News 15 Apr 2025
    Bình Dương Province is hosting the International Tennis Federation (ITF) J30 Bình Dương 2025 for young talents on April 14-27 ... As one of the competitions of the ITF, points gained will be used to level up the players in their world junior rankings.
    Edit

    Anup Jalota Honored With Padma Shri Mahendra Kapoor Award At ITFS Awards 2025

    MENA FN 14 Apr 2025
    (MENAFN - IANS) Mumbai, April 13 (IANS) Veteran singer Anup Jalota was recently honored with the prestigious Padma Shri Mahendra Kapoor Award at the ITFS Awards 2025. He was joined by legendary ... .
    Edit

    Abubakar off to winning start in ITF Juniors

    The News International 14 Apr 2025
    Tennis player Abubakar Talha playing a shot. — Facebook@AbTalhachamp/File ... Local lad Abubakar Talha got off to a winning start in the ITF Pakistan World Juniors Tennis Championship 2025 Leg-II which started here at the PTF Tennis Complex Monday ... .
    Edit

    Singer Anup Jalota Receives Padma Shri Mahendra Kapoor Award At ITFS Awards 2025

    News18 13 Apr 2025
    Anup Jalota received the Padma Shri Mahendra Kapoor Award at the ITFS Awards 2025 in Mumbai, celebrating his achievements and Mahendra Kapoor's legacy, with Sidhant Kapoor performing ... .
    Edit

    Coupon Payment (ITF Group AD)

    Public Technologies 11 Apr 2025
    ) Coupon Payment ... Company. ITF Group AD (ITFB) ... - Issuer. ITF Group AD. - BSE code. ITFB ... ITF Group AD published this content on April 11, 2025, and is solely responsible for the information contained herein.
    Edit

    Pakistan trio make quarters at ITF Juniors

    Dawn 09 Apr 2025
    ISLAMABAD. Pakis­tan players Nadir Mirza, Amir Mazari, and Abuba­kar Talha moved into the boys’ singles quarter-finals of the ITF Pakistan Zainab Ali Naqvi Mem­orial World Juniors Tennis Championship here at the PTF Complex on Tuesday ... Boys’ singles ... .
    Edit

    Nadir and Abubakar in ITF Tennis semis

    The News International 09 Apr 2025
    Nadir Mirza and Abubakar Talha entered semis-finals of the ITF Pakistan Zainab Ali Naqvi Memorial World Juniors Tennis Championship Leg-1 following contrasting wins at the PTF Tennis Complex Wednesday.
    Edit

    Insider information (ITF Group AD)

    Public Technologies 07 Apr 2025
    ITF Group AD published this content on April 07, 2025, and is solely responsible for the information contained ...
    ×