Bookbinding

Bookbinding is the process of physically assembling a book from an ordered stack of paper sheets that are folded together into sections or sometimes left as a stack of individual sheets. The stack is then bound together along one edge by either sewing with thread through the folds or by a layer of flexible adhesive. For protection, the bound stack is either wrapped in a flexible cover or attached to stiff boards. Finally, an attractive cover is adhered to the boards and a label with identifying information is attached to the covers along with additional decoration. Book artists or specialists in book decoration can greatly expand the previous explanation to include book like objects of visual art with high value and artistic merit of exceptional quality in addition to the book's content of text and illustrations.

Bookbinding is a specialized trade that relies on basic operations of measuring, cutting, and gluing. A finished book depends on a minimum of about two dozen operations to complete but sometimes more than double that according to the specific style and materials. All operations have a specific order and each one relies on accurate completion of the previous step with little room for back tracking. An extremely durable binding can be achieved by using the best hand techniques and finest materials when compared to a common publisher's binding that falls apart after normal use.

Thorns, spines, and prickles

In plant morphology, thorns, spines, prickles, and in general spinose structures (as spinose teeth, spinose apical process) are all hard structures with sharp, stiff ends, generally with the same function of physically deterring animals from eating the plant material.

In common language the terms are used more or less interchangeably, but in botanical terms, thorns are derived from shoots (so they can be branched or not, they can have leaves or not, and they arise from a bud), spines are derived from leaves (the entire leaf or some part of the leaf that has vascular bundles inside, like the petiole or a stipule), and prickles are derived from the epidermis (so they can be found anywhere on the plant, and do not have vascular bundles inside so they can be removed more easily and cleanly than thorns and spines).

Leaf margins also may have teeth, and if those teeth are sharp, they are called spinose teeth on a spinose leaf margin (some authors consider them a kind of spine). On a leaf apex, if there is an apical process (generally an extension of the midvein), and if it is specially sharp, stiff, and spinelike, it can be called spinose or pungent apical process (again, some authors call them a kind of spine). When epidermis is covered with very long, stiff trichomes (more correctly called bristles in this case, for some authors a kind of prickle) is called hispid vestiture, if is covered with stinging trichomes it can be called urent vestiture.

SPINE (molecular biology)

SPINE stands for Strep-protein interaction experiment. SPINE is a powerful tool to detect protein-protein interactions in vivo. The bait protein has to be expressed with a Strep-tag under the conditions when the potential interaction partners are presumably present in the cells. The addition of formaldehyde links the bait protein to its potential interaction partners. The bait protein together with its potential interaction partners can then be isolated using a Streptactin sepharose column. The cross-links between the bait protein and the potential interaction partner can be cleaved by heating the samples in Laemmli buffer. Finally, the co-purified interaction partner can be separated by SDS PAGE and identified by mass spectrometry.

References

Introduction

Introduction, The Introduction, Intro, or The Intro may refer to:

Intro (R&B group)

Intro is an American R&B trio from Brooklyn, New York City, New York. The trio consisted of members Jeff Sanders, Clinton "Buddy" Wike and lead singer/songwriter Kenny Greene. Intro released two albums (for Atlantic Records): 1993's Intro and their second album, 1995's New Life. The group had a string of US hits in the 1990s. The hits included the singles "Let Me Be The One", the Stevie Wonder cover "Ribbon in the Sky", "Funny How Time Flies" and their highest charting hit, "Come Inside".

Intro's Kenny Greene died from complications of AIDS in 2001. Intro recently emerged as a quintet consisting of Clinton "Buddy" Wike, Jeff Sanders, Ramon Adams and Eric Pruitt. Adams departed in 2014, with the group back down to its lineup as a trio. They are currently recording a new album to be released in 2015. The group released a new single in 2013 called "I Didn't Sleep With Her" and a new single "Lucky" in October 2014.

Discography

Albums

Singles

References

Introduction (music)

In music, the introduction is a passage or section which opens a movement or a separate piece, preceding the theme or lyrics. In popular music this is often abbreviated as intro. The introduction establishes melodic, harmonic, and/or rhythmic material related to the main body of a piece.

Introductions may consist of an ostinato that is used in the following music, an important chord or progression that establishes the tonality and groove for the following music, or they may be important but disguised or out-of-context motivic or thematic material. As such the introduction may be the first statement of primary or other important material, may be related to but different from the primary or other important material, or may bear little relation to any other material.

A common introduction to a rubato ballad is a dominant seventh chord with fermata, Play  an introduction that works for many songs is the last four or eight measures of the song, Play  while a common introduction to the twelve-bar blues is a single chorus. Play